Single article

DOI: 10.47026/2413-4864-2022-4-108-120

Grigoreva E.A., Gordova V.S., Sergeeva V.E.

The Effect of Silicon Nanoparticles and Water-Soluble Silicates on the Liver (comparison of our own research results with the literature data)

Keywords: silicon, amorphous silicon dioxide, silica, silicates, silicoses, liver, drinking water

This literature review combines data on the effect of silicon compounds on the body – silicon nanoparticles and water-soluble silicates, obtained by domestic and foreign researchers over the past decade. a widespread use of amorphous silicon dioxide in modern industry, as well as revision of regulatory documents on silicon content in drinking water in the Russian Federation give this aspect special relevance. Increased attention is paid to comparing our own results of long-term experiments on silicon intake with drinking water by laboratory animals and the literature data. It has been shown that morphological changes in the liver caused by exposure to water-soluble silicates and nanoparticles are similar. Thus, questions about the biological inertness of silicon, monitoring the use of silicon in industry, and adjustment of its maximum permissible concentration in drinking water require further study.


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About authors

Grigoreva Evgeniia A.
Post-Graduate Student of Biology and Microbiology Department, Chuvash State University, Russia, Cheboksary (; ORCID:
Gordova Valentina S.
Candidate of Medical Sciences, Assistant Professor of Fundamental Medicine Department, Immanuel Kant Baltic Federal University, Russia, Kaliningrad (; ORCID:
Sergeeva Valentina E.
Doctor of Biological Sciences, Professor, Department of Medical Biology with a course in Microbiology and Virology, Chuvash State University, Russia, Cheboksary (; ORCID:

Article link

Grigoreva E.A., Gordova V.S., Sergeeva V.E. The Effect of Silicon Nanoparticles and Water-Soluble Silicates on the Liver (comparison of our own research results with the literature data) [Electronic resource] // Acta medica Eurasica. – 2022. – №4. P. 108-120. – URL: DOI: 10.47026/2413-4864-2022-4-108-120.