Single article

DOI: 10.47026/2413-4864-2022-3-79-84

Stepanov V.G., Timofeeva L.A., Nasrullayev M.N., Yusova M.A.

Difficulties in Differential Diagnosis of Thyroid Nodular Pathology. A Case Report

Keywords: thyroid nodular formation, multiparametric ultrasound examination, sonoelastography, ultrasound with enhanced contrast

This paper presents a clinical case of follicular thyroid cancer, the importance of multiparametric ultrasound in the early detection of thyroid cancer is shown. To diagnose follicular thyroid cancer, multiparametric ultrasound examination was performed in B-mode, color Doppler mapping mode, sonoelastography and in contrast enhancement mode. Based on the results, indications for fine needle aspiration puncture biopsy were determined and further management tactics for the patient with follicular thyroid cancer were determined. Thus, a timely diagnosis and a correct chosen tactics for treating follicular thyroid cancer resulted in a favorable disease outcome.

References

  1. Aleksandrov Yu.K., Yanovskaya E.A., Shubin L.B., Dyakiv A.D. Effektivnoststratifikatsionnykh sistem v diagnostike uzlovykh zabolevanii shchitovidnoi zhelezy [Effectiveness of stratification systems in the diagnosis of nodular diseases of the thyroid gland]. Problemy endokrinologii, 2019, vol. 65(4), pp. 216–226. DOI: https://doi.org/10.14341/probl10087.
  2. Belyakov I.E., Aleksandrov Yu.K., Yanovskaya E.A., Yanovskaya M.E. Kompleksnaya otsenka pri uzlovoi patologii shchitovidnoi zhelezy [Comprehensive assessment of nodular pathology of the thyroid gland]. Zdorov’e i obrazovanie, 2017, vol. 19, no. 8, pp. 13–17.
  3. Zhelonkina N.V., Poitina A.S., Pol’kin V.V. et al. Vozmozhnosti ekhografii v differentsial’noi diagnostike follikulyarnykh opukholei shchitovidnoi zhelezy [Possibilities of echography in the differential diagnosis of follicular tumors of the thyroid gland]. Radiatsiya i risk (Byulleten’ Natsional’nogo radiatsionno-epidemiologicheskogo registra), 2016, vol. 25(3), pp. 35–45. DOI: 10.21870/0131-3878-2016-25-3-35-45.
  4. Sencha A.N., Sencha E.A., Penyaeva E.I., Timofeeva L.A. Ul’trazvukovoe issledovanie shchitovidnoi zhelezy. Shag za shagom. Ot prostogo k slozhnomu [Ultrasound examination of the thyroid gland. Step by step. From simple to complex]. Moscow, MEDpress-inform Publ., 2019, 208 p.
  5. Sencha A.N., Sencha E.A., Penyaeva E.I., Fedotkina E.P., Bikeev Yu.V., Timofeeva L.A. Ul’trazvukovye kontrasty v ekhografii [Ultrasonic contrasts in echography]. Prakticheskaya meditsina, 2018, no. 1(112), pp. 74–80.
  6. Sinyukova G.T., Gudilina E.A., Danzanova T.Yu., Sholokhov V.N. et al. Sovremennye tekhnologii ul’trazvukovoi vizualizatsii v diagnostike mestnogo retsidiva raka shchitovidnoi zhelezy [Modern ultrasound imaging technologies in the diagnosis of local recurrence of thyroid cancer]. Mezhdunarodnyi nauchno-issledovatel’skii zhurnal, 2016, vol. 9-3(51), pp. 81–84.
  7. Tamazyan T.S. Ul’trazvukovye kriterii differentsial’noi diagnostiki follikulyarnykh opukholei shchitovidnoi zhelezy [Ultrasound criteria for differential diagnosis of follicular tumors of the thyroid gland]. Digital Diagnostics, 2021, vol. 2, no. S1, pp. 22–23. DOI: 10.17816/DD20211s22.
  8. Timofeeva L.A., Aleksandrov Yu.K., Tukhbatullin M.G., Aleshina T.N., Sencha E.A. Obosnovanie primeneniya ul’trazvukovogo issledovaniya s ispol’zovaniem kontrastnykh preparatov pri opukholyakh shchitovidnoi zhelezy [Rationale for the use of ultrasound using contrast agents for thyroid tumors]. Rossiiskii elektronnyi zhurnal luchevoi diagnostiki, 2021, no. 11(2), pp. 115–121.
  9. Timofeeva L.A., Sencha A.N., Tukhbatullin M.G., Shubin L.B. Sovremennye aspekty ul’trazvukovoi elastografii v differentsial’noi diagnostike uzlovykh novoobrazovanii shchitovidnoi zhelezy [Modern aspects of ultrasound elastography in the differential diagnosis of nodular neoplasms of the thyroid gland]. Rossiiskii elektronnyi zhurnal luchevoi diagnostiki, 2019, vol. 9(3), pp. 30–40. DOI: 10.21569/2222-7415-2019-9-3-30-40.
  10. Borowczyk M., Woliński K., Więckowska B., Jodłowska-Siewert E. et al. Sonographic Features Differentiating Follicular Thyroid Cancer from Follicular Adenoma-A Meta-Analysis. Cancers (Basel), 2021, vol. 13(5), p. 938. DOI: 10.3390/cancers13050938.
  11. Dighe, M., Barr R., Bojunga J., Cantisani V. et al. Thyroid Ultrasound: State of the Art. Part 2 – Focal Thyroid Lesions. Medical Ultrasonography, 2017, vol. 19, no. 2, pp. 195–210. DOI: 10.11152/mu-999.
  12. Gharib H. Does iodine cause thyroid cancer? Acta Endocrinol (Buchar), 2018, vol. 14(4), pp. 525–526. DOI: 10.4183/aeb.2018.525.
  13. Liu B.J., Zhang Y.F., Zhao C.K., Wang H.X. et al. Conventional ultrasound characteristics, TI-RADS category and shear wave speed measurement between follicular adenoma and follicular thyroid carcinoma. Hemorheol. Microcirc., 2020, vol. 75, pp. 291–301. DOI: 10.3233/CH-190750.
  14. Tugendsam C., Petz V., Buchinger W., Schmoll-Hauer B. et al. Ultrasound criteria for risk stratification of thyroid nodules in the previously iodine deficient area of Austria – a single centre, retrospective analysis. Thyroid Res., 2018, vol. 11, p. 3. DOI: 10.1186/s13044-018-0047-8.
  15. Zhang J.Z., Hu B. Sonographic features of thyroid follicular carcinoma in comparison with thyroid follicular adenoma. J Ultrasound Med., 2014, vol. 33, pp. 221–227.

About authors

Stepanov Vladimir G.
Minister, Ministry of Health of the Chuvash Republic, Russia, Cheboksary (medicin_prm@cap.ru; )
Timofeeva Lyubov A.
Doctor of Medical Sciences, Professor, Department of Propedaedeutics of Internal Diseases with Radio Diagnosis Course, Chuvash State University, Russia, Cheboksary (adabai@mail.ru; ORCID: https://orcid.org/0000-0002-4707-8214)
Nasrullayev Magomed N.
Doctor of Medical Sciences, Professor, Department of Surgery, Kazan State Medical Academy, Russia, Kazan (msh.avia@yandex.ru; ORCID: https://orcid.org/0000-0001-6176-9372)
Yusova Marina A.
Candidate of Medical Sciences, Associate Professor, Department of Propaedeutics of Internal Diseases with a Course of Radiology, Chuvash State University, Russia, Cheboksary (yusova2012@mail.ru; ORCID: https://orcid.org/0000-0002-8034-5337)

Article link

Stepanov V.G., Timofeeva L.A., Nasrullayev M.N., Yusova M.A. Difficulties in Differential Diagnosis of Thyroid Nodular Pathology. A Case Report [Electronic resource] // Acta medica Eurasica. – 2022. – №3. P. 79-84. – URL: https://acta-medica-eurasica.ru/en/single/2022/3/10/. DOI: 10.47026/2413-4864-2022-3-79-84.