Single article

DOI: 10.47026/2413-4864-2021-4-73-78

Timofeeva L.A., Aleshina T.N., Baranova M.E., Yusova M.A., Nikolaeva N.N.

Informative value of sonoelastography in the differential diagnosis of follicular thyroid cancer

Keywords: multiparametric ultrasound examination, strain elastography, shear wave elastography, follicular thyroid cancer

In recent years, the opportunities of radiation diagnostic methods have stepped far ahead and today they play a leading role at the stage of preoperative diagnosis of thyroid diseases. The most promising of them is multiparametric ultrasound examination, as well as sonoelastography associated with it. Strain elastography and shear wave elastography make it possible to determine the boundaries of pathological formation and quantitative characteristics of nodular stiffness, which is important when determining the boundaries of invasive tumor growth, primarily thyroid cancer, when planning an upcoming surgical intervention. The article describes a clinical case of radiation diagnosis made for follicular thyroid cancer; it shows the importance of multiparametric ultrasound, including sonoelastography, in the early detection of thyroid cancer. A timely diagnosis and a correct chosen tactics for treating follicular thyroid cancer resulted in a favorable disease outcome.

References

  1. Aleksandrov Yu.K., Yanovskaya E.A., Shubin L.B., Dyakiv A.D. Effektivnost’ stratifikatsionnykh sistem v diagnostike uzlovykh zabolevanii shchitovidnoi zhelezy [The effec-tiveness of risk stratification systems in diagnosis of nodular thyroid disorders]. Problems of Endocrinology, 2019, vol. 65, no. 4, pp. 216–226. DOI: https://doi.org/10.14341/probl10087.
  2. Borsukov A.V. Byt’ ili ne byt’ TIRADS: polemicheskie zametki s Evraziiskogo foruma po raku shchitovidnoi zhelezy [TI-RADS: to be or not to be. Polemic notes from the Eurasian Forum on thyroid cancer]. Endocrine Surger, 2016, vol. 10, no. 3, pp. 33–36.
  3. Zhelonkina N.V., Poitina A.S., Pol’kin V.V. et al. Vozmozhnosti ekhografii v differentsial’noi diagnostike follikulyarnykh opukholei shchitovidnoi zhelezy [The Potentialities of Echography in the Differential Diagnosis of Thyroid Follicular Tumors]. Radiatsiya i risk (Byulleten’ Natsional’nogo radiatsionno-epidemiologicheskogo registra), 2016, vol. 25, no. 3, pp. 35–45. DOI: 10.21870/0131-3878-2016-25-3-35-45.
  4. Mit’kov V.V. Prakticheskoe rukovodstvo po ul’trazvukovoi diagnostike. Obshchaya ul’trazvukovaya diagnostika. 3-e izd., pererab. i dop. [Practical guide to ultrasound diag-nostics. General ultrasound diagnostics. 3rd]. Moscow, Vidar-M Publ., 2019, 756 p.
  5. Sencha A.N., Sencha E.A., Penyaeva E.I., Timofeeva L.A. Ul’trazvukovoe issledovanie shchitovidnoi zhelezy. Shag za shagom. Ot prostogo k slozhnomu [Ultrasound examination of the thyroid gland. Step by step. From simple to complex]. Moscow, MEDpress-inform Publ., 2019, 208 p.
  6. Sinyukova G.T., Gudilina E.A., Danzanova T.Yu., Sholokhov V.N., Lepedatu P.I., Allakhverdieva G.F., Kostyakova L.A., Berdnikov S.N. Sovremennye tekhnologii ul’trazvukovoi vizualizatsii v diagnostike mestnogo retsidiva raka shchitovidnoi zhelezy [Modern Technologies of Ultrasound Imaging in the Diagnostics of Local Recurrence of Thyroid Carcinoma]. Mezhdunarodnyi nauchno-issledovatel’skii zhurnal, 2016, vol. 9-3, no. 51, pp. 81–84.
  7. Tamazyan T.S. Ul’trazvukovye kriterii differentsial’noi diagnostiki follikulyarnykh opukholei shchitovidnoi zhelezy [Ultrasound Criteria for Differential Diagnosis of Follicular Thyroid Tumors]. Digital Diagnostics, 2021, vol. 2, no. S1, pp. 22–23. DOI: 10.17816/DD20211s22.
  8. Timofeeva L.A. Diagnosticheskaya taktika pri uzlovykh obrazovaniyakh shchitovidnoi zhelezy [Diagnostic tactics for thyroid nodules]. Kazanskii meditsinskii zhurnal, 2012, vol. 93, no. 1, pp. 103–107.
  9. Timofeeva L.A., Sencha A.N., Tukhbatullin M.G., Shubin L.B. Sovremennye aspekty ul’trazvukovoi elastografii v differentsial’noi diagnostike uzlovykh novoobrazovanii shchitovidnoi zhelezy [Modern aspects of ultrasound elastography in the differential diagnosis of nodular neoplasms of the thyroid gland]. Rossiiskii elektronnyi zhurnal luchevoi diagnostiki, 2019, vol. 9, no. 3, pp. 30–40. DOI: 10.21569/2222-7415-2019-9-3-30-40.
  10. Tukhbatullin M.G., Safiullina L.R., Galeeva Z.M., Khamzina F.T. et al. Ekhografiya v dia-gnostike zabolevanii vnutrennikh i poverkhnostno raspolozhennykh organov [Echography in the diagnosis of diseases of internal and superficially located organs]. Kazan, Meditsinskaya kniga Publ., 2016, 208 p.
  11. Borowczyk M., Woliński K., Więckowska B., Jodłowska-Siewert E., Szczepanek-Parulska E., Verburg F.A., Ruchała M. Sonographic Features Differentiating Follicular Thyroid Cancer from Follicular Adenoma-A Meta-Analysis. Cancers (Basel), 2021, vol. 24, no. 13(5), p. 938. DOI: 10.3390/cancers13050938.
  12. Kuo T.C., Wu M.H., Chen K.Y., Hsieh M.S., Chen A., Chen C.N. Ultrasonographic features for differentiating follicular thyroid carcinoma and follicular adenoma. Asian J Surg., 2020, vol. 43, no. 1, pp. 339–346. DOI: 10.1016/j.asjsur.2019.04.016.
  13. Li W., Song Q., Lan Y., Li J., Zhang Y., Yan L., Li Y., Zhang Y., Luo Y. The Value of Sonogra-phy in Distinguishing Follicular Thyroid Carcinoma from Adenoma. Cancer Manag Res., 2021, vol. 17, no. 13, pp. 3991–4002. DOI: 10.2147/CMAR.S307166.
  14. Ou D., Yao J., Jin J., Yan M., Shi K., Zheng Q., Yang C., Xu D. Ultrasonic identification and regression analysis of 294 thyroid follicular tumors. J Cancer Res Ther., 2020, vol. 16, no. 5, pp. 1056–1062. DOI: 10.4103/jcrt.JCRT_913_19.
  15. Sencha A.N., Patrunov Yu.N., Pavlovich S.V., Timofeyeva L.A., Tukhbatullin M.G., Smetnik A.A. Current State of the Problem of Thyroid Diseases: Principles and Technology of Thyroid Ultrasound. In: Thyroid Ultrasound. From Simple to Complex. Cham, Springer Verlag, 2019, pp. 1–38.
  16. Seo J.K., Kim Y.J., Kim K.G., Shin I., Shin J.H., Kwak J.Y. Differentiation of the Follicular Ne-oplasm on the Gray-Scale US by Image Selection Subsampling along with the Marginal Outline Using Convolutional Neural Network. Biomed Res Int., 2017, vol. 2017, Arti-cle ID 3098293. DOI: 10.1155/2017/3098293.

About authors

Timofeeva Lyubov A.
Doctor of Medical Sciences, Professor, Department of Propedaedeutics of Internal Diseases with Radio Diagnosis Course, Chuvash State University, Russia, Cheboksary (adabai@mail.ru; ORCID: https://orcid.org/0000-0002-4707-8214)
Aleshina Tatiana N.
Assistant Lecturer, Department of Propedaedeutics of Internal Diseases with Radio Diagnosis Course, Chuvash State University, Russia, Cheboksary (brunetka08-87@mail.ru; ORCID: https://orcid.org/0000-0002-5068-7598)
Baranova Marina E.
Head of the Department of Radiation Diagnostics, Radiologist, Emergency Hospital, Russia, Cheboksary (bsmp@med.cap.ru; )
Yusova Marina A.
Post-Graduate Student, Department of Propedaedeutics of Internal Diseases with Radio Diagnosis Course, Chuvash State University, Russia, Cheboksary (yusova2012@mail.ru; ORCID: https://orcid.org/0000-0002-8034-5337)
Nikolaeva Natalia N.
Head of Centralized Cytological Laboratory, Doctor of Clinical Laboratory Diagnostics, Republican Clinical Oncology Dispensary, Russia, Cheboksary (rkod@med.cap.ru; )

Article link

Timofeeva L.A., Aleshina T.N., Baranova M.E., Yusova M.A., Nikolaeva N.N. Informative value of sonoelastography in the differential diagnosis of follicular thyroid cancer [Electronic resource] // Acta medica Eurasica. – 2021. – №4. P. 73-78. – URL: https://acta-medica-eurasica.ru/en/single/2021/4/8/. DOI: 10.47026/2413-4864-2021-4-73-78.