Single article

Sergeeva V., Gordova V., Pavlova O., Smorodchenko A.

The Contribution of Professor Dina Semyonovna Gordon’s Scientific School to Studying Thymic Morphology and Functions (Scientific-Historical Overview)

Keywords: thymus, neuromediators, adaptation, immuno-histochemical methods

The article contains a review of literature devoted to the primary lymphoid organ – the thymus; it also reflects the contribution of Professor Dina Semenovna Gordon’s scientific school to the study of this organ. The main methodological stages in studying the thymus are traced; methods of studying the thymic structures in experiments under various influences are indicated. The Department of General Biology and Histology of the Chuvash State University Medical Faculty was founded in 1968. The research direction of the department was the study of lymphoid organs by means of luminescent-histochemical methods which made it possible to reveal adrenergic nerve fibers in the thymus as well as cells containing neurally mediated biogenic amines. Integrated approach to the study of the thymus was formed by researchers of scientific school of Professor Dina Semenovna Gordon during twenty years. It included several histochemical methods. Subsequently, they were substituted by immuno-histochemical methods and luminescent-histochemical methods of Falk-Hillarp and Cross were modified taking into account the achievements of modern science and they are used in an integrated methodological approach to the study of the thymus at present time.

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About authors

Smorchenko Alina Tikhonovna
Anatomy Center private associate professor, University Hospital Charit, Germany, Berlin )
Pavlova Olga Vitalyevna
medical biology with a course of microbiology and virology department graduate student, Chuvash State University, Russia, Cheboksary (olgavitaljevn@mail.ru; )
Gordova Valentina S.
Candidate of Medical Sciences, Associate Professor, Department
of Fundamental Medicine, Immanuel Kant Baltic Federal University, Russia, Kaliningrad (crataegi@rambler.ru; ORCID: https://orcid.org/0000-0001-5109-9862)
Sergeeva Valentina E.
Doctor of Biological Sciences, Professor, Department of Medical Biology with a course in Microbiology and Virology, Chuvash State University, Russia, Cheboksary (kaf-biology@yandex.ru; ORCID: https://orcid.org/0000-0003-3471-5226)

Article link

Sergeeva V., Gordova V., Pavlova O., Smorodchenko A. The Contribution of Professor Dina Semyonovna Gordon’s Scientific School to Studying Thymic Morphology and Functions (Scientific-Historical Overview) [Electronic resource] // Acta medica Eurasica. – 2019. – №2. P. 52-63. – URL: https://acta-medica-eurasica.ru/en/single/2019/2/7/.