Статья журнала

Ильина Л.Ю., Ефейкина Н.Б.

Тучные клетки и амилоидогенез

Ключевые слова: тучные клетки, амилоид, плазмациты, В-лимфоциты, поджелудочная железа, болезнь Альцгеймера

Обобщены литературные сведения за период с 1970 г. по 2016 г. о роли тучных клеток в процессе образования амилоидного белка. Рассмотрены вопросы участия тучных клеток в патогенезе разных вариантов амилоидоза. Обобщены литературные данные о взаимодействии тучных клеток с другими клетками в процессе амилоидогенеза. Сделан вывод, что тучные клетки могут быть индикаторами образования амилоидных отложений как в головном мозге, так и в других органах. Кроме того, они могут играть критическую роль в начале и прогрессировании болезни Альцгеймера.

Ilyina L., Efeykina N.

Mast cells and amyloidogenesis

Keywords: mast cells, amyloid, plasmacytes, b-lymphocytes, pancreas, Alzheimer's disease

Literature data for the period 1970 to 2016 on the role of mast cells in the process of amyloid protein formation were summarized. The questions of mast cells participation in the processes of amyloidogenesis were examined. Literature data on interaction of mast cells with other cells in the process of amyloidogenesis were summarized. It was concluded that mast cells can be indicators of amyloid deposits formation both in the brain and in other organs. In addition, they can play a critical role in Alzheimer's disease onset and progression.

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Сведения об авторах

Ильина Лилия Юрьевна
старший преподаватель кафедры медицинской биологии с курсом микробиологии и вирусологии, Чувашский государственный университет, Россия, Чебоксары (lileaceae@rambler.ru)
Ефейкина Надежда Борисовна
кандидат биологических наук, доцент кафедры медицинской биологии с курсом микробиологии и вирусологии, Чувашский государственный университет, Россия, Чебоксары (nadezhdaefeykina@yandex.ru)

Ссылка на статью

Ильина Л.Ю., Ефейкина Н.Б. Тучные клетки и амилоидогенез [Электронный ресурс] // Acta medica Eurasica. – 2016. – №4. – С. 41-50. – URL: http://acta-medica-eurasica.ru/single/2016/4/8/.