Статья журнала

Голенков А.В.

Эффективность лечения и профилактики табачной зависимости по результатам исследований Кокрейновского сотрудничества

Ключевые слова: отказ от табакокурения, лечение табачной зависимости, профилактика табакокурения

В обзоре рассмотрен широкий спектр различных вмешательств для лечения и профилактики табачной зависимости (ТЗ). В анализ включены 33 рандомизированных контролируемых исследования по отказу от табакокурения (ТК) 2012-2016 гг., взятых из базы данных Кокрейновского сотрудничества. Для мотивации к отказу от ТК используются: совет врача, медсестры, индивидуальное консультирование, вовлечение в лечебные группы, интервью при непосредственном контакте, по телефону, Интернету, средствам массовой информации (масс-медиа), проведение биомедицинских тестов. Фармакотерапия в первую очередь включала никотинзаместительную терапию, варениклин, антидепрессанты (Бупропион, Нортриптилин), а также опиодные антагонисты и никотиновую вакцину. Из прочих методов упоминается акупунктура. Профилактика ТК ориентирована на подрастающее поколение, проводится в школе и семьях. Эффективность лечения ТЗ и профилактики ТК пока низкая, что должно побуждать к продолжению исследований.

Golenkov A.

Efficiency of nicotine dependence treatment and prevention by results of cochrane collaboration’s researches

Keywords: smoking cessation, treatment of nicotine dependence, smoking prevention

A wide range of various interventions for nicotine dependence (ND) treatment and prevention is considered in the review. The analysis includes 33 randomized controlled studies for smoking cessation performed in 2012–2016 taken from the database of Cochrane Collaboration. To motivate for smoking cessation doctor’s and nurse’s advice, individual consultation, involvement in medical groups, interview at direct contact, by phone, via Internet, mass media and, biomedical tests are used. Pharmacotherapy included first of all nicotine replacement therapy, varenicline, antidepressants (bupropion, nortriptyline) as well as opioid antagonists and a nicotine vaccine. Among other methods acupuncture is mentioned. Smoking prevention is focused on younger generation; it is carried out at schools and in families. Efficiency of ND treatment and smoking prevention is still low which should encourage continuing studies.

Литература

  1. Голенков А.В. Табакокурение при шизофрении: частный вопрос или глобальная проблема? // Наркология. 2010. № 11. С. 57–64.
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  7. Прекращение потребления табака и лечение табачной зависимости: научно обоснованные рекомендации / под ред. А.К. Дёмина; РАПСИГО; CSPP. М.; Вашингтон, 2013. 244 с.
  8. Bala M.M., Strzeszynski L., Topor-Madry R., Cahill K. Mass media interventions for smoking cessation in adults. Cochrane Database Syst. Rev. 2013. Jun. 6; 6: CD004704. doi: 10.1002/ 14651858.CD004704.pub3.
  9. Bize R., Burnand B., Mueller Y., Rège-Walther M., Camain J.Y., Cornuz J. Biomedical risk assessment as an aid for smoking cessation. Cochrane Database Syst. Rev. 2012. Dec. 12; 12: CD004705. doi: 10.1002/14651858.CD004705.pub4.
  10. Boyle R., Solberg L., Fiore M. Use of electronic health records to support smoking cessation. Cochrane Database Syst. Rev. 2014. Dec. 30; 12: CD008743. doi: 10.1002/14651858.CD008743.pub3.
  11. Cahill K., Hartmann-Boyce J., Perera R. Incentives for smoking cessation. Cochrane Database Syst Rev. 2015 May. 18; 5: CD004307. doi: 10.1002/14651858.CD004307.pub5.
  12. Cahill K., Lancaster T. Workplace interventions for smoking cessation. Cochrane Database Syst. Rev. 2014. Feb. 26; 2: CD003440. doi: 10.1002/14651858.CD003440.pub4.
  13. Cahill K., Stevens S., Perera R., Lancaster T. Pharmacological interventions for smoking cessation: an overview and network meta-analysis. Cochrane Database Syst. Rev. 2013. May. 31; 5: CD009329. doi: 10.1002/14651858.CD009329.pub2.
  14. Civljak M., Stead L.F., Hartmann-Boyce J., Sheikh A., Car J. Internet-based interventions for smoking cessation. Cochrane Database Syst. Rev. 2013. Jul. 10; 7: CD007078. doi: 10.1002/ 14651858.CD007078.pub4.
  15. Coppo A., Galanti M.R., Giordano L., Buscemi D., Bremberg S., Faggiano F. School policies for preventing smoking among young people. Cochrane Database Syst. Rev. 2014. Oct. 24; 10: CD009990. doi: 10.1002/14651858.CD009990.pub2.
  16. David S.P., Lancaster T., Stead L.F., Evins A.E., Prochaska J.J. Opioid antagonists for smoking cessation. Cochrane Database Syst. Rev. 2013. Jun. 6; 6: CD003086. doi: 10.1002/ 14651858.CD003086.pub3.
  17. Farley A.C.,Hajek P., Lycett D., Aveyard P. Interventions for preventing weight gain after smoking cessation. Cochrane Database Syst. Rev. 2012. Jan. 18; 1: CD006219. doi: 10.1002/ 14651858.CD006219.pub3.
  18. Frazer K., Callinan J.E., McHugh J., van Baarsel S., Clarke A., Doherty K., Kelleher C. Legislative smoking bans for reducing harms from secondhand smoke exposure, smoking prevalence and tobacco consumption. Cochrane Database Syst. Rev. 2016 Feb. 4; 2: CD005992. doi: 10.1002/ 14651858.CD005992.pub3.
  19. Hajek P., Stead L.F., West R., Jarvis M., Hartmann-Boyce J., Lancaster T. Relapse prevention interventions for smoking cessation. Cochrane Database Syst. Rev. 2013. Aug. 20; 8: CD003999. doi: 10.1002/14651858.CD003999.pub4.
  20. Hartmann-Boyce J., Cahill K., Hatsukami D., Cornuz J. Nicotine vaccines for smoking cessation. Cochrane Database Syst. Rev. 2012. Aug. 15; 8: CD007072. doi: 10.1002/14651858. CD007072.pub2.
  21. Hartmann-Boyce J., Lancaster T., Stead L.F. Print-based self-help interventions for smoking cessation. Cochrane Database Syst. Rev. 2014. Jun. 3; 6: CD001118. doi: 10.1002/14651858.CD001118.pub3.
  22. Hollands G.J., McDermott M.S., Lindson-Hawley N., Vogt F., Farley A., Aveyard P. Interventions to increase adherence to medications for tobacco dependence. Cochrane Database Syst. Rev. 2015. Feb. 23; 2: CD009164. doi: 10.1002/14651858.CD009164.pub2.
  23. Hughes J.R., Stead L.F., Hartmann-Boyce J., Cahill K., Lancaster T. Antidepressants for smoking cessation. Cochrane Database Syst. Rev. 2014. Jan. 8; 1: CD000031. doi: 10.1002/ 14651858.CD000031.pub4.
  24. Lindson-Hawley N., Aveyard P., Hughes J.R. Reduction versus abrupt cessation in smokers who want to quit. Cochrane Database Syst. Rev. Nov. 14; 11: CD008033. doi: 10.1002/ 14651858.CD008033.pub3.
  25. Lindson-Hawley N., Thompson T.P., Begh R. Motivational interviewing for smoking cessation. Cochrane Database Syst. Rev. 2015. Mar. 2; 3: CD006936. doi: 10.1002/14651858.CD006936.pub3.
  26. Marcano Belisario J.S., Bruggeling M.N., Gunn L.H., Brusamento S., Car J. Interventions for recruiting smokers into cessation programmes. Cochrane Database Syst. Rev. Dec. 12; 12: CD009187. doi: 10.1002/14651858.CD009187.pub2.
  27. Van der Meer R.M., Willemsen M.C., Smit F., Cuijpers P. Smoking cessation interventions for smokers with current or past depression. Cochrane Database Syst. Rev. Aug. 21; 8: CD006102. doi: 10.1002/14651858.CD006102.pub2.
  28. McRobbie H., Bullen C., Hartmann-Boyce J., Hajek P. Electronic cigarettes for smoking cessation and reduction. Cochrane Database Syst. Rev. 2014. 12: CD010216. doi: 10.1002/14651858. CD010216.pub2.
  29. Park E.W., Tudiver F.G., Campbell T. Enhancing partner support to improve smoking cessation. Cochrane Database Syst. Rev. 2012. Jul. 11; 7: CD002928. doi: 10.1002/14651858. CD002928.pub3.
  30. Rice V.H., Hartmann-Boyce J., Stead L.F. Nursing interventions for smoking cessation. Cochrane Database Syst. Rev. 2013. Aug. 12; 8: CD001188. doi: 10.1002/14651858.CD001188.pub4.
  31. Stanton A., Grimshaw G. Tobacco cessation interventions for young people. Cochrane Database Syst. Rev. 2013. Aug. 23; 8: CD003289. doi: 10.1002/14651858.CD003289.pub5.
  32. Stead L.F., Buitrago D., Preciado N., Sanchez G., Hartmann-Boyce J., Lancaster T. Physician advice for smoking cessation. Cochrane Database Syst. Rev. 2013. May. 31; 5: CD000165. doi: 10.1002/14651858.CD000165.pub4.
  33. Stead L.F., Hartmann-Boyce J., Perera R., Lancaster T. Telephone counselling for smoking cessation. Cochrane Database Syst. Rev. 2013. Aug. 12; 8: CD002850. doi: 10.1002/14651858. CD002850.pub3.
  34. Stead L.F., Koilpillai P., Fanshawe T.R., Lancaster T. Combined pharmacotherapy and behavioural interventions for smoking cessation. Cochrane Database Syst. Rev. 2016. Mar. 24; 3: CD008286. doi: 10.1002/14651858.CD008286.pub3.
  35. Stead L.F., Koilpillai P., Lancaster T. Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation. Cochrane Database Syst. Rev. 2015. Oct. 12; 10: CD009670. doi: 10.1002/14651858.CD009670.pub3.
  36. Stead L.F., Lancaster T. Behavioural interventions as adjuncts to pharmacotherapy for smoking cessation. Cochrane Database Syst. Rev. 2012. Dec. 12; 12: CD009670. doi: 10.1002/14651858. CD009670.pub2.
  37. Thomas R.E., Baker P.R., Thomas B.C., Lorenzetti D.L. Family-based programmes for preventing smoking by children and adolescents. Cochrane Database Syst. Rev. 2015. Feb. 27; 2: CD004493. doi: 10.1002/14651858.CD004493.pub3.
  38. Thomas R.E., McLellan J., Perera R. School-based programmes for preventing smoking. Cochrane Database Syst. Rev. 2013. Apr. 30; 4: CD001293. doi: 10.1002/14651858.CD001293.pub3.
  39. Ussher M.H., Taylor A.H., Faulkner G.E. Exercise interventions for smoking cessation. Cochrane Database Syst. Rev. 2014. Aug. 29; 8: CD002295. doi: 10.1002/14651858.CD002295.pub5.
  40. White A.R., Rampes H., Liu J.P., Stead L.F., Campbell J. Acupuncture and related interventions for smoking cessation. Cochrane Database Syst. Rev. 2014. Jan. 23; 1: CD000009. doi: 10.1002/14651858.CD000009.pub4.
  41. http://www.cochrane.org/ ru/about-us.

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  19. Hajek P., Stead L.F., West R., Jarvis M., Hartmann-Boyce J., Lancaster T. Relapse prevention interventions for smoking cessation. Cochrane Database Syst. Rev., 2013, Aug. 20, 8, CD003999. doi: 10.1002/14651858.CD003999.pub4.
  20. Hartmann-Boyce J., Cahill K., Hatsukami D., Cornuz J. Nicotine vaccines for smoking cessation. Cochrane Database Syst. Rev., 2012, Aug. 15, 8, CD007072. doi: 10.1002/14651858. CD007072.pub2.
  21. Hartmann-Boyce J., Lancaster T., Stead L.F. Print-based self-help interventions for smoking cessation. Cochrane Database Syst. Rev., 2014, Jun. 3, 6, CD001118. doi: 10.1002/14651858. CD001118.pub3.
  22. Hollands G.J., McDermott M.S., Lindson-Hawley N., Vogt F., Farley A., Aveyard P. Interventions to increase adherence to medications for tobacco dependence. Cochrane Database Syst. Rev., 2015, Feb. 23, 2, CD009164. doi: 10.1002/14651858.CD009164.pub2.
  23. Hughes J.R., Stead L.F., Hartmann-Boyce J., Cahill K., Lancaster T. Antidepressants for smoking cessation. Cochrane Database Syst. Rev., 2014, Jan. 8, 1, CD000031. doi: 10.1002/ 14651858.CD000031.pub4.
  24. Lindson-Hawley N., Aveyard P., Hughes J.R. Reduction versus abrupt cessation in smokers who want to quit. Cochrane Database Syst. Rev., 2012, Nov. 14, 11, CD008033. doi: 10.1002/ 14651858.CD008033.pub3.
  25. Lindson-Hawley N., Thompson T.P., Begh R. Motivational interviewing for smoking cessation. Cochrane Database Syst. Rev., 2015, Mar. 2, 3, CD006936. doi: 10.1002/14651858. CD006936.pub3.
  26. Marcano Belisario J.S., Bruggeling M.N., Gunn L.H., Brusamento S., Car J. Interventions for recruiting smokers into cessation programmes. Cochrane Database Syst. Rev., 2012, Dec. 12, 12, CD009187. doi: 10.1002/14651858.CD009187.pub2.
  27. Van der Meer R.M., Willemsen M.C., Smit F., Cuijpers P. Smoking cessation interventions for smokers with current or past depression. Cochrane Database Syst. Rev., 2013, Aug. 21, 8, CD006102. doi: 10.1002/14651858.CD006102.pub2.
  28. McRobbie H., Bullen C., Hartmann-Boyce J., Hajek P. Electronic cigarettes for smoking cessation and reduction. Cochrane Database Syst. Rev., 2014, 12, CD010216. doi: 10.1002/ 14651858. CD010216.pub2.
  29. Park E.W., Tudiver F.G., Campbell T. Enhancing partner support to improve smoking cessation. Cochrane Database Syst. Rev., 2012, Jul. 11, 7, CD002928. doi: 10.1002/14651858. CD002928.pub3.
  30. Rice V.H., Hartmann-Boyce J., Stead L.F. Nursing interventions for smoking cessation. Cochrane Database Syst. Rev., 2013, Aug. 12, 8,CD001188. doi: 10.1002/14651858.CD001188. pub4.
  31. Stanton A., Grimshaw G. Tobacco cessation interventions for young people. Cochrane Database Syst. Rev., 2013, Aug. 23, 8, CD003289. doi: 10.1002/14651858.CD003289.pub5.
  32. Stead L.F., Buitrago D., Preciado N., Sanchez G., Hartmann-Boyce J., Lancaster T. Physician advice for smoking cessation. Cochrane Database Syst. Rev., 2013, May. 31, 5, CD000165. doi: 10.1002/14651858.CD000165.pub4.
  33. Stead L.F., Hartmann-Boyce J., Perera R., Lancaster T. Telephone counselling for smoking cessation. Cochrane Database Syst. Rev., 2013, Aug. 12, 8, CD002850. doi: 10.1002/14651858. CD002850.pub3.
  34. Stead L.F., Koilpillai P., Fanshawe T.R., Lancaster T. Combined pharmacotherapy and behavioural interventions for smoking cessation. Cochrane Database Syst. Rev., 2016, Mar. 24, 3, CD008286. doi: 10.1002/14651858.CD008286.pub3.
  35. Stead L.F., Koilpillai P., Lancaster T. Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation. Cochrane Database Syst. Rev., 2015, Oct. 12, 10, CD009670. doi: 10.1002/14651858.CD009670.pub3.
  36. Stead L.F., Lancaster T. Behavioural interventions as adjuncts to pharmacotherapy for smoking cessation. Cochrane Database Syst. Rev., 2012, Dec. 12, 12, CD009670. doi: 10.1002/ 14651858. CD009670.pub2.
  37. Thomas R.E., Baker P.R., Thomas B.C., Lorenzetti D.L. Family-based programmes for preventing smoking by children and adolescents. Cochrane Database Syst. Rev., 2015, Feb. 27, 2, CD004493. doi: 10.1002/14651858.CD004493.pub3.
  38. Thomas R.E., McLellan J., Perera R. School-based programmes for preventing smoking. Cochrane Database Syst. Rev., 2013, Apr.30, 4, CD001293. doi: 10.1002/14651858.CD001293.pub3.
  39. Ussher M.H., Taylor A.H., Faulkner G.E. Exercise interventions for smoking cessation. Cochrane Database Syst. Rev., 2014, Aug. 29, 8, CD002295. doi: 10.1002/14651858.CD002295. pub5.
  40. White A.R., Rampes H., Liu J.P., Stead L.F., Campbell J. Acupuncture and related interventions for smoking cessation. Cochrane Database Syst. Rev., 2014, Jan. 23, 1, CD000009. doi: 10.1002/14651858.CD000009.pub4.
  41. http://www.cochrane.org/ ru/about-us.

Сведения об авторах

Голенков Андрей Васильевич
доктор медицинских наук, профессор, заведующий кафедрой психиатрии, медицинской психологии и неврологии, Чувашский государственный университет, Россия, Чебоксары (golenkovav@inbox.ru)

Ссылка на статью

Голенков А.В. Эффективность лечения и профилактики табачной зависимости по результатам исследований Кокрейновского сотрудничества [Электронный ресурс] // Acta medica Eurasica. – 2016. – №3. – С. 1-10. – URL: http://acta-medica-eurasica.ru/single/2016/3/1/.