Single article

Sergeeva V., Gordova V., Pavlova O., Smorodchenko A.

The Contribution of Professor Dina Semyonovna Gordon’s Scientific School to Studying Thymic Morphology and Functions (Scientific-Historical Overview)

Keywords: thymus, neuromediators, adaptation, immuno-histochemical methods

The article contains a review of literature devoted to the primary lymphoid organ – the thymus; it also reflects the contribution of Professor Dina Semenovna Gordon’s scientific school to the study of this organ. The main methodological stages in studying the thymus are traced; methods of studying the thymic structures in experiments under various influences are indicated. The Department of General Biology and Histology of the Chuvash State University Medical Faculty was founded in 1968. The research direction of the department was the study of lymphoid organs by means of luminescent-histochemical methods which made it possible to reveal adrenergic nerve fibers in the thymus as well as cells containing neurally mediated biogenic amines. Integrated approach to the study of the thymus was formed by researchers of scientific school of Professor Dina Semenovna Gordon during twenty years. It included several histochemical methods. Subsequently, they were substituted by immuno-histochemical methods and luminescent-histochemical methods of Falk-Hillarp and Cross were modified taking into account the achievements of modern science and they are used in an integrated methodological approach to the study of the thymus at present time.

References

  1. Artem’yeva I.L., Sergeeva V.E. Somatostatin-pozitivnyye struktury timusa [Somatostatin-positive structures of the thymus]. Vestnik Chuvashskogo universiteta, 2013, no. 3, pp. 368–371.
  2. Banin V.V., Belousova T.A., Bykov V.L., Dubovaya T.K., Zaitsev V.B., Zashikhin A.L., Kapitonova M.Yu., Kuznetsov S.L., Nozdrin V.I., Samusev R.P., Semchenko V.V., Stadnikov A.A., Torbek V.E., Chelyshev Yu.A. Terminologia Histologica. Mezhdunarodnye terminy po tsitologii i gistologii cheloveka s ofitsial’nym spiskom russkikh ekvivalentov [Terminologia Histologica. International terms of Cytology and histology of the human from the official list of Russian equivalents]. Moscow, GEOTAR-Media , 2009, 272 p.
  3. Gistokhimiya v morfologii [Histochemistry in morphology]. Cheboksary, Chuvash State University Publ., 2013, 168 p.
  4. Gordova V.S. Neiromediatory limfoidnykh organov (funktsional’naya morfologiya) [Neurotransmitters of lymphoid organs (functional morphology)]. Zdravookhranenie Chuvashii, 2013, no. 4, pp. 92–96.
  5. Gordova V.S., Ivanova E.P., Sergeeva V.E. Tuchnyye kletki pri okraske toluidinovym sinim v eksperimente [Properties of toluidine blue stained mast cells in the experiment with the intake of soluble silicon]. Vestnik Baltiyskogo federal’nogo universiteta im. I. Kanta. Ser. Yestestvennyye i meditsinskiye nauki, 2018, no. 2, pp. 97–104.
  6. Gordova V.S., Basova L.A., Smorodchenko A.D., Sergeeva V.E. Preimushchestva ispol’zovaniya metodiki s primeneniyem «Avidin-Alexa Fluor® 488» pri izuchenii tuchnykh kletok v organakh laboratornykh gryzunov [Advantages of using the technique with the use of “Avidin-Alexa Fluor® 488” in the study of mast cells in the organs of laboratory rodents]. Allergologiya i immunologiya, 2015, vol. 16, no. 4, p. 406.
  7. Gordova V.S., Sergeeva V.E. Prodolzhenie uchenogo – v ego uchenikakh [The task of high school professor is to nurture deserving scolars]. In: Universitetskoe obrazovanie v polietnicheskikh regionakh Povolzh’ya: k 50-letiyu Chuvashskogo gosudarstvennogo universiteta imeni I.N. Ul’yanova (VI Arsent’evskie chteniya): sb. st. [University education in the polyethnic regions of the Volga region: to the 50th anniversary of the Chuvash State University named after I.N. Ulyanov (VI Arsentiev readings). Digest of articles]. Cheboksary, 2015, pp. 336–339.
  8. Gordon B.M. Matematicheskoe obosnovanie spetsifichnosti lyuminestsentno-gistokhimicheskikh reaktsii na autolyuminestsiruyushchikh strukturakh [Mathematical substantiation of specificity of luminescent-histochemical reactions on autoluminescent structures]. In: Morfologiya i gistokhimiya tkanei v norme, patologii i eksperimente: sb. st. [Morphology and histochemistry of tissues in norm, pathology and experiment: Collected papers]. Cheboksary, Chuvash State University Publ., 1982, pp. 71–76.
  9. Gordon B.M. Tsitobioaminnaya sistema timusa i adaptatsiya [Thymus cytobioamine system and adaptation]. Cheboksary, Chuvash State University Publ., 2000, 242 p.
  10. Gordon D.S. Moi ucheniki [My scholars]. In: Morfologiya v teorii i praktike: mater. Vseros. nauch.-prakt. konf. s mezhdunar. uchastiem, posv. 95-letiyu so dnya rozhdeniya d-ra med. nauk, professora D.S. Gordon. (Cheboksary, 22 noyabrya 2017 g.) [Morphology in theory and practice: Proc. of conf. to the 95th anniversary of D.S. Gordon (Cheboksary, 22 november 2017)]. Cheboksary, Chuvash State University Publ., 2017, iss. 2, pp. 9–64.
  11. Gordon D.S. Ya v moem mire [I am in my world] Morfologiya v teorii i praktike: sb. mater. i tez. k 90-letiyu so dnya rozhdeniya D.S. Gordon [Morphology in theory and practice: Proc. of conf. to the 90th anniversary of D.S. Gordon]. Cheboksary, Chuvash State University Publ., 2012, pp. 6–117.
  12. Gordon D.S., Sergeeva V.E., Zelenova I.G. Neiromediatory limfoidnykh organov [Neurotransmitters of lymphoid organs]. Leningrad, Nauka Publ, 1982, 128 p.
  13. Gordon D.S., Sergeeva V.E., Golubeva N.N. Aktivnost’ i raspredelenie biogennykh aminov v strukturakh timusa i selezenki pri vvedenii izo- i geterologichnykh eritrotsitov [Activity and distribution of biogenic amines in thymus and spleen structures when introducing iso- and heterologous erythrocytes]. Byulleten’ eksperimental’noi biologii i meditsiny, 1978, no. 8, pp. 245–247.
  14. Gordon D.S., Sergeeva V.E., Golubeva N.N. Gistokhimicheskie kriterii otsenki neiromediatornogo statusa limfoidnykh organov pri antigennom i nespetsificheskom vozdeistviyakh na organism [Histochemical criteria for evaluating the neurotransmitter status of lymphoid organs in antigenic and nonspecific effects on the body]. Regulyatsiya immunnogo gomeostaza: sb. materialov III Vsesoyuz. simpoz. [Proc. of 3rd USSR Conf. «Regulation of immune homeostasis»]. Leningrad, 1982, pp. 12–13.
  15. Gordon D.S., Bogomolova I.L., Sergeeva V.E. Nekotorye gistokhimicheskie pokazateli limfoidnoi tkani pri peresadke serdtsa, konservirovannogo formal’degidom [Some histochemical indices of lymphoid tissue during cardiac transplantation preserved with formaldehyde]. Trudy II Moskovskogo med. in-ta: sbornik. trudov, 1978, vol. 113, no. 23, pp. 146–147.
  16. Gordon D.S., Sergeeva V.E., Smorodchenko A.T., Kirillov N.A., Petrova T.L., Olangin O.I., Spirin I.V. Fluorestsiruyushchiye granulyarnyye kletki timusa, identifitsiruyemyye kak dendriticheskiye makrofagi [Thymus fluorescent granular cells identified as dendritic macrophages]. Byulleten’ eksperimental’noi biologii i meditsiny, 2001, vol. 131, no. 7, pp. 118–120.
  17. Gordon D.S., Sergeeva V.E., Smorodchenko A.T., Petrova T.L., Olangin O.I., Il’ina L.Yu., Belyayeva V.S., Serova O.V., Mardar’yev A.N., Spirin I.V., Yastrebova S.A., Struchko G.Yu. Morfologicheskaya reaktsiya dendritnykh i tuchnykh kletok timusa na immunosupressiyu i immunostimulyatsiyu [Morphological reaction of dendritic and mast cells of the thymus to immunosuppression and immunostimulation]. International Journal on Immunorehabilitation, 2000, vol. 2, no. 2, p. 51.
  18. Gordon D.S., Sergeeva V.E., Yastrebova S.A., Il’ina L.Yu., Belyayeva V.S., Serova O.V. Lyuminestsentnaya morfologiya bioaminov timusa v usloviyakh immunosupressii [Luminescent morphology of thymus bioamines under immunosuppression conditions]. International Journal on Immunorehabilitation, 1999, no. 4, p. 81.
  19. D’yachkova I.M., Luzikova E.M., Sergeeva V.E. Issledovaniye neyrospetsificheskoy enolazy, belkov MHC II-klassa i kal’tsiysvyazyvayushchikh molekul makrofagov timusa [Study of neurospecific enolase, MHC proteins of class II and calcium-binding molecules of thymus macrophages]. Morfologiya, 2009, no. 4, pp. 90–91.
  20. Karnaukhov V.N. Lyuminestsentnyi spektral’nyi analiz kletki [Luminescent spectral analysis of the cell]. Moscow, Nauka Publ, 1978, 207 p.
  21. Krokhina E.M., Aleksandrov P.N. Simpaticheskii (adrenergicheskii) komponent efferentnoi innervatsii serdechnoi myshtsy [Sympathetic (adrenergic) component of efferent innervation of the cardiac muscle]. Kardiologiya, 1969, no. 3, pp. 97–104.
  22. Lyubovtseva L.A., Gordon D.S. Tkanevaya lokalizatsiya gistamina v strukturakh vilochkovoi zhelezy [Tissue localization of histamine in the structures of the thymus gland]. Makro-mikrostruktura tkanei v norme, patologii i eksperimente: sb. st. [Macro-microstructure of tissues in norm, pathology and experiment: Collected papers]. Cheboksary, Chuvash State University Publ., 1976, iss. 3, pp. 18–21.
  23. Lyubovtseva L.A., Gordon D.S. Lyuminestsentno-gistokhimicheskii analiz gistaminsoderzhashchikh kletok timusnoi dol’ki [Luminescence-histochemical analysis of histamine-containing cells of the thymus lobe]. Arkhiv anatomii, gistologii i embriologii, 1988, vol. XIV, no. 11, p. 61.
  24. Lyubovtseva L.A., Mamaladze A.A., Bochkarev V.A. Soderzhanie gistamina i tsitokhimiya vilochkovoi zhelezy pri vvedenii bradikinina i atsetilkholina [The histamine content and cytochemistry of the thymus gland with the introduction of bradykinin and acetylcholine]. Makro-mikrostruktura tkanei v norme, patologii i eksperimente: sb. st. [Macro-microstructure of tissues in norm, pathology and experiment: Collected papers]. Cheboksary, Chuvash State University Publ., 1979, pp. 40–44.
  25. Luzikova E.M., Gordova V.S., Prokhorova A.I., Timofeev A.S., Smorodchenko A.D., Sergeeva V.E. Sochetannoe ispol’zovanie metoda Fal’ka-Khillarpa i avidina s flyuorestsiruyushchimi metkami pri izuchenii stroeniya timusa [The combined use of the Falk – Hillarp and avidin method with fluorescent labels in the study of thymus structure]. Morfologiya [Morphology], 2017, vol. 151, no. 3, p. 85.
  26. Luzikova E.M., Oganesyan L.V., Kulakova K.S., Sergeeva V.E. Vliyaniye melatonina na BCL-2 sistemu selezonki i timusa v raznykh svetovykh usloviyakh [The effect of melatonin on the BCL-2 system of the spleen and thymus in different light conditions]. Vestnik novykh meditsinskikh tekhnologiy, 2018, no. 4, pp. 265–271. Available at: http://medtsu.tula.ru/VNMT/Bulletin/E2018-4/e2018-4.pdf.
  27. Petrova T.L., Sergeeva V.E. Neyromediatornoye obespecheniye mikrostruktur timusa pri ovarioektomii i estrogennom vozdeystvii [Neurotransmitter provision of thymus microstructures during ovariectomy and estrogenic effects]. Cheboksary, Chuvash State University Publ., 2002, 130 p.
  28. Sarilova I.L., Sergeeva V.E., Smorodchenko A.T. Effekt testektomii na struktury vilochkovoy zhelezy, ekspressiruyushchiye glavnyy kompleks gistosovmestimosti II klassa [Effect of testectomy on thymus gland structures expressing the main class II histocompatibility] // Byulleten’ eksperimental’noi biologii i meditsiny [Bulletin of Experimental Biology and Medicine], 2008, V. 145, no. 1, pp. 103–106.
  29. Sergeeva V.E. Dina Semenovna Gordon: razvitie ee idei v morfologii [Dina S. Gordon: development of her idea in morphology]. Morfologiya v teorii i praktike: sb. mater. i tez. k 90-letiyu so dnya rozhdeniya D.S. Gordon [Proc. of Conf. «Morphology in theory and practice»]. Cheboksary, Chuvash State University Publ., 2012, pp. 118–129.
  30. Sergeeva V.E. Voploshcheniye idey Diny Semenovny prodolzhayetsya… [Realization of the of Dina Semenovna’s ideas continues…] // Morfologiya v teorii i praktike: mater. Vseros. nauch.-prakt. konf. s mezhdunar. uchastiem, posv. 95-letiyu so dnya rozhdeniya d-ra med. nauk, professora D.S. Gordon. (Cheboksary, 22 noyabrya 2017 g.) [Morphology in theory and practice: Proc. of conf. to the 95th anniversary of D.S. Gordon (Cheboksary, 22 november 2017)]. Cheboksary, Chuvash State University Publ., 2017, iss. 2, pp. 65–71.
  31. Sergeeva V.E. Vyyavleniye nervnykh komponentov zobnoy zhelezy, okrashennykh metilenovoy sin’yu [Identification of the nervous components of the goiter, stained with methylene blue]. Rukopis’ deponirovana v VINITI ot 25.10.1972 g. № 4660-72 [Manuscript deposited in VINITI dated 10.25.1972, No. 4660-72].
  32. Sergeeva V.E. Adrenoretseptornye svoistva telets Gassalya zobnoi zhelezy [Adrenoretseptorial properties of Gassal’s corpuscles of the thymus gland]. Byulleten’ eksperimental’noi biologii i meditsiny, 1972, no. 6, p. 121.
  33. Sergeeva V.E. Gistotopografiya katekholaminov zobnoi zhelezy mlekopitayushchikh [Histotopography of catecholamines of the mammalian thymus gland]. Byulleten’ eksperimental’noi biologii I meditsiny, 1974, no. 4, p. 115.
  34. Sergeeva V.E. Vliyaniye serotonina na autolyuminestsiruyushchiye i adrenergicheskiye struktury zobnoy zhelezy [The influence of serotonin on autoluminescent and adrenergic structures of the thymus gland]. Problemy endokrinologii, 1974, no. 3, 98.
  35. Sergeeva V.E. Vliyaniye rezerpina na nervnyy apparat i nekotoryye kletochnyye struktury zobnoy zhelezy [Effect of reserpine on the nervous apparatus and some cellular structures of the thymus]. In: Makro-mikrostruktura tkanei v norme, patologii i eksperimente: sb. st. [Macro-microstructure of tissues in norm, pathology and experiment: Collected papers]. Cheboksary, Chuvash State University Publ., 1975, pp. 78–84.
  36. Sergeeva V.E. Kolichestvennyy i kachestvennyy analiz monoaminov adrenergicheskikh struktur vilochkovoy zhelezy [Quantitative and qualitative analysis of monoamines adrenergic thymus gland structures]. In; Makro-mikrostruktura tkanei v norme, patologii i eksperimente: sb. st. [Macro-microstructure of tissues in norm, pathology and experiment: Collected papers]. Cheboksary, Chuvash State University Publ., 1979, pp. 11–13.
  37. Sergeeva V.E. Sezonnyye izmeneniya aminosoderzhashchikh struktur timusa v pervyy chas antigennogo vozdeystviya [Seasonal changes in the amine-containing structures of the thymus in the first hour of antigenic exposure]. Byulleten’ eksperimental’noi biologii i meditsiny, 1992, vol. 113, no. 3, pp. 311–315.
  38. Sergeeva V.E. Lyuminestsentno-gistokhimicheskaya kharakteristika rannei reaktsii monoaminsoderzhashchikh struktur timusa na antigennye vozdeistviya [Luminescence-histochemical characteristics of the early reaction of monoamine-containing thymus structures to antigenic effects]. Morfologiya, 1993, no. 5-6, p. 65–73.
  39. Sergeeva V.E., Gordova V.S. K yubileyu Diny Semenovny Gordon [On the anniversary of Dina Semyonovna Gordon]. Morfologiya, 2017, vol. 151, no. 2, pp. 95–96.
  40. Sergeeva V.E., Gordova V.S., Gordon D.S. Lyuminestsentnaya gistokhimiya biogennych aminov v morfofunktsional’nom sostojanii organov i tkanei v eksperimente (nauchno-istoricheskij obzor) [Elektronnyj resurs] [Luminescent histochemistry of biogenic amines in the morphofunctional state of organs and tissues in an experiment (scientific and historical review) [Electronic resource]. Acta medica Eurasica. no. 3. pp. 39–49. Available at: http://acta-medica-eurasica.ru/single/2017/3/6.
  41. Sergeeva V.E., Gordon D.S. Lyuminestsentno-gistokhimicheskaya kharakteristika rannei reaktsii monoaminsoderzhashchikh struktur timusa na antigennye vozdeistviya [Luminescence-histochemical characteristics of the early reaction of monoamine-containing thymus structures to antigenic effects]. Cheboksary, Chuvash State University Publ., 1992, 352 p.
  42. Sergeeva V.E., Gordon D.S., Gunin A.G. Sochetaniye svoystv makrofagov i kletok APUD-serii v monoaminosoderzhashchikh premedullyarnykh kletkakh timusnoy dol’ki [The combination of the properties of macrophages and cells APUD-series in monoamine-containing premedullary cells of the thymic lobule]. Morfologiya, 1994, vol. 106, no. 1-3, pp. 159–163.
  43. Sergeeva V.E., Dzamashvili K.S., Timofeeva G.M. Vnutriorgannaya innervatsiya timusa s differentsirovannym vyyavleniem vegetativnykh komponentov [In-organ innervation of the thymus with differentiated detection of vegetative components]. Arkhiv anatomii, gistologii i embriologii, 1974, vol. 67, no. 6, pp. 56–59.
  44. Sergeeva V.E., Klyasheva R.I., Aleksandrova N.V., Porfir’yeva S.A. Vliyaniye gidrokortizona na soderzhaniye aminov v timuse [Effect of hydrocortisone on the content of amines in the thymus]. Byulleten’ eksperimental’noi biologii i meditsiny, 1997, vol. 123, no. 6, pp. 677–679.
  45. Sergeeva V.E., Markina V.M., Skvortsova I.V. Aktivnost’ fosfataz v vilochkovoy zheleze [Phosphatase activity in the thymus gland]. Makro-mikrostruktura tkanei v norme, patologii i eksperimente: sb. st. [Macro-microstructure of tissues in norm, pathology and experiment: Collected papers]. Cheboksary, Chuvash State University Publ., 1976, pp. 16–18.
  46. Sergeeva V.E., Muzykantskii E.L., Bogomolova I.E. Izuchenie vilochkovoi zhelezy pri peresadke serdtsa, obrabotannogo formalinom [Study of thymus gland during heart transplant treated with formalin]. In: Makro-mikrostruktura tkanei v norme, patologii i eksperimente: sb. st. [Macro-microstructure of tissues in norm, pathology and experiment: Collected papers]. Cheboksary, Chuvash State University Publ., 1979, pp. 14–17.
  47. Sergeeva V.E., Naumova E.M. Gistokhimicheskiy analiz populyatsiy tuchnykh kletok timusa myshey pri vvedenii AKTG [Histochemical analysis of mouse thymus mast cell populations with the introduction of ACTH]. Byulleten’ eksperimental’noi biologii i meditsiny, 2004, vol. 13, no. 7, pp. 107–111.
  48. Sergeyeva V.E., Perepelkina A.V., Sarilova I.V. Serotoninovyy indeks v strukturakh timusa, soderzhashchikh biogennyye aminy, pri vvedenii testosterona [Serotonin index in thymus structures containing biogenic amines, with the introduction of testosterone]. Morfologiya, 2006, vol. 130, no. 5, p. 80.
  49. Sergeyeva V.E., Sarilova I.L. Reaktsiya monoaminsoderzhashchikh struktur timusa na eksperimental’nuyu testektomiyu [The reaction of monoamine-containing structures of the thymus on experimental testectomy]. Byulleten’ eksperimental’noi biologii i meditsiny, 2005, vol. 140, no. 11, pp. 574–576.
  50. Sergeeva V.E., Spirin I.V. Reaktsiya serotoninsoderzhashchikh struktur timusa na vvedeniye somatotropnogo gormona [Reaction of serotonin-containing structures of the thymus to the introduction of somatotropic hormone]. Rossiyskiye morfologicheskiye vedomosti, 1999, no. 1-2, p. 133.
  51. Smirnova T.L., Sergeeva V.E. Struktura populyatsii tuchnykh kletok timusa pri ovarioektomii i estrogennom vozdeystvii [Population of thymus mast cells during ovariectomy and estrogenic effects]. Morfologiya v teorii i praktike: sb. mater. i tez. k 90-letiyu so dnya rozhdeniya D.S. Gordon [Proc. of Conf. «Morphology in theory and practice»]. Cheboksary, Chuvash State University Publ., 2012, pp. 270–272.
  52. Spirin I.V., Sergeeva V.E. Kolebanie kontsentratsii serotonina, katecholovykh aminov I gistamina v structurakh timusa pri vvedenii somatotropnogo gormona [Fluctuation of the concentration of serotonin, catecholamines and histamine in the thymic structures during introduction of somatotropic hormone]. In: Babukhinskie chteniya: materialy 4-i nauch.-prakt. konf. (Orel. 2005) [Proc. of 4th Conf. «Babukhin Readings» (Orel, 2005)]. Moscow, Retinoidy Publ., 2005, p. 129.
  53. Shatskikh O.A., Luzikova E.M., Sergeyeva V.E. Reaktsiya CD1A- i CD3-pozitivnykh kletok timusa pri vvedenii melatonina v razlichnykh svetovykh usloviyakh [The reaction of CD1A- and CD3-positive thymus cells with the introduction of melatonin in different light conditions]. Sovremennyye problemy nauki i obrazovaniya, 2015, no. 5, p. 40.
  54. Shatskikh O.A., Sergeyeva V.E. Issledovaniye korrelyatsionnykh otnosheniy mezhdu bioaminami v strukturakh timusa pri vvedenii melatonina [The study of the correlation between bioamines in the structures of the thymus with the introduction of melatonin]. Mezhdunarodnyy nauchno-issledovatel’skiy zhurnal, 2013, no. 6-3(13), pp. 65–66.
  55. Yalaletdinova L.R., Gordova V.S., Yastrebova S.A., Sergeyeva V.E. Morfologicheskaya kharakteristika timusa neberemennykh myshey pri vvedenii khorionicheskogo gonadotropina [Morphological characteristics of nonpregnant mice thymus at chorionic gonadotropin injection]. Acta medica Eurasica, 2016, no. 3. pp. 59–65. Available at: http://acta-medica-eurasica.ru/single/2016/3/10.
  56. Yalaletdinova L.R., Gordova V.S., Yastrebova S.A., Sergeeva V.E. Neiroimmunomoduliruyushchie svoistva khorionicheskogo gonadotropina [Neuroimmunomodulating properties of the chorionic gonadotropin]. Cheboksary, Chuvash State University Publ., 2016, pp. 60–62.
  57. Yastrebova S.A., Illarionova S.V., Zaytseva N.A., Sergeyeva V.E. Reaktsiya CD68 pozitivnykh kletok selezenki i timusa na vvedeniye immunomodulyatorov [The reaction of CD68 positive cells of the spleen and thymus to the introduction of immunomodulators]. Mezhdunarodnyy zhurnal prikladnykh i fundamental’nykh issledovaniy, 2016, no. 4-3, pp. 589–593.
  58. Cross S.W.D., Ewen S.W.B., Rost F.W.D. A study of the methods available for the cytochemical localisation of histamine by fluorescence induced with o-phthalaldehyde or acetaldehyde. J., 1971, vol. 3, pp. 471–476.
  59. Falck B., Hillarp N.-Å., Thieme G., Torp A. Fluorescence of catecholamines and related compounds condensed with formaldehyde. Journal of Histochemistry & Cytochemistry, 1965, vol. 10, Iss. 3, pp. 348–354.
  60. Gordova V.S., Dyachkova I.M., Sergeeva V.E., Sapozhnikov S.P., Smorodchenko A.T. Morphofunctional adaptation of rat thymus structures to silicon consumption with drinking water // Bulletin Sergeeva V.E., Gordova V.S. K yubileyu Diny Semenovny Gordon[On the anniversary of Dina Semyonovna Gordon]. Morfologiya [Morphology], 2017, vol. 151, no. 2, pp. 95–96.

About authors

Smorchenko Alina Tikhonovna
Anatomy Center private associate professor, University Hospital Charit, Germany, Berlin
Pavlova Olga Vitalyevna
medical biology with a course of microbiology and virology department graduate student, Chuvash State University, Russia, Cheboksary (olgavitaljevn@mail.ru)
Gordova Valentina Sergeevna
candidate of medical sciences, fundamental medicine department associate professor, Immanuel Kant Baltic Federal University, Russia, Kaliningrad (crataegi@rambler.ru)
Sergeeva Valentina E.
Doctor of Biological Sciences, Professor, Department of Medical Biology with a course in Microbiology and Virology, Chuvash State University, Russia, Cheboksary (kaf-biology@yandex.ru)

Article link

Sergeeva V., Gordova V., Pavlova O., Smorodchenko A. The Contribution of Professor Dina Semyonovna Gordon’s Scientific School to Studying Thymic Morphology and Functions (Scientific-Historical Overview) [Electronic resource] // Acta medica Eurasica. – 2019. – №2. P. 52-63. – URL: http://acta-medica-eurasica.ru/en/single/2019/2/7/