Single article

Kostrova O., Stomenskaya I., Struchko G., Timofeeva N., Nikiforova N., Sergeeva K., Razbirina E.

Changes in a Myelogram Against the Background of Leukemia

Keywords: acute leukemia, chronic leukemia, myelogram, blood cells, leuko-erythroblastic ratio, neutrophil maturation index

The paper analyzes the results of 136 patients study with various forms of leukemia. Leukemia was detected in 47 women and 89 men. 69 people were diagnosed with acute leukemia, 67 – with chronic one. Among acute forms, myeloblastic leukemia was found in 30,4% of those examined, lymphoblastic – in 14,5%, undifferentiated leukemia – 50,7%, promyelocytic leukemia was detected in 4,3%. Among chronic forms, myelocytic leukemia was detected in 16,4% of patients, lymphocytic leukemia – in 77,6%, and monocytic, hairy cell leukemia and osteomyelofibrosis in one case each. The average age of patients with acute leukemia was 44,9±1,7 years, those with chronic leukemia – 61,1±1,3 years. When calculating various indices in both acute and chronic leukemia, the data turned out to be ambiguous. A decline in the neutrophil maturation index predominated, most likely as a result of cytostatic therapy. A simultaneous increase in the leuko-erythroblastic ratio may indicate a significant dilution of bone marrow punctate.

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About authors

Kostrova Olga Yu.
Candidate of Medical Sciences, Assistant Professor, Head of Department of the Instrumental Diagnostics with a Course of Phthisiology, Chuvash State University, Russia, Cheboksary (evkbiz@yandex.ru)
Stomenskaya Irina S.
Candidate of Medical Sciences, Assistant Professor, Department of the Instrumental Diagnostics with a Course of Phthisiology, Chuvash State University, Russia, Cheboksary (irina.stomenskaja@gmail.com)
Struchko Gleb Yu.
Doctor of Medical Sciences, Professor, Head of Normal and Topographic Anatomy Department, Chuvash State University, Russia, Cheboksary (glebstr@mail.ru)
Timofeeva Natalya Yu.
Assistant Lecturer, Department of Instrumental Diagnostics Department with a Course of Phthisiology, Chuvash State University, Russia, Cheboksary (bla11blabla@yandex.ru)
Nikiforova Natalya Valeryevna
Centralized Clinical Diagnostic Laboratory head, Republican Clinical Hospital, Russia, Cheboksary
Sergeeva Kristina Yurievna
Central Clinical Diagnostic Laboratory clinical laboratory diagnostics doctor, Republican Clinical Hospital, Russia, Cheboksary
Razbirina Ekaterina A.
Student of Medical Faculty, Chuvash State University, Russia, Cheboksary (razbirinae@mail.ru)

Article link

Kostrova O., Stomenskaya I., Struchko G., Timofeeva N., Nikiforova N., Sergeeva K., Razbirina E. Changes in a Myelogram Against the Background of Leukemia [Electronic resource] // Acta medica Eurasica. – 2019. – №2. P. 44-51. – URL: http://acta-medica-eurasica.ru/en/single/2019/2/6/.