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Mukhametdinova L.M., Tukhbatullin M.G., Fomina E.E.
The Importance of Ultrasound Examination of Renal Allograft
Keywords: renal allograft, resistance index, shear wave ultrasound elastography, stiffness of the renal transplant parenchyma
Kidney transplantation is an effective method of treating patients with end-stage chronic renal failure, as it improves the quality of life and has advantages in patient survival compared with dialysis methods of substitutive renal therapy. To date, ultrasound examination (ultrasound) is the most common diagnostic method for assessing the morphological state of a kidney transplant. Shear wave ultrasound elastography serves as an additional method for assessing the stiffness of the renal allograft parenchyma and early diagnosis of its dysfunction. The aim of the study was to determine the correlation dependence of blood flow parameters, laboratory parameters and stiffness of the kidney transplant parenchyma at different periods. Materials and methods. The study group included 112 patients aged 18 to 59 years who underwent kidney transplantation. Each patient underwent ultrasound examination in B-mode and color Doppler imaging mode. The stiffness of the renal transplant parenchyma was determined using shear wave ultrasound elastography. The functional state of the kidney transplant was assessed by blood serum creatinine and urea levels. Research results. Laboratory results were compared with parenchymal stiffness and renal graft resistance index. In the early postoperative period, a moderate correlation was found (rxy = 0.301) between creatinine level and parenchymal stiffness and a weak correlation (rxy > 0.3) between creatinine level and resistance index, as well as between urea level and resistance index and parenchymal stiffness. Conclusions. Ultrasound examination makes it possible to evaluate hemodynamics in kidney transplants at different periods, which correlates with urea and creatinine levels in blood serum.
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About authors
- Mukhametdinova Landysh M.
- Ultrasound Diagnostic Doctor, Department of Ultrasound Investigation № 1, Republican Clinical Hospital; Post-Graduate Student, Department of Ultrasound Diagnostics, Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Russia, Kazan (minnullovnalm@mail.ru; ORCID: https://orcid.org/0009-0000-5716-184X)
- Tukhbatullin Munir G.
- Doctor of Medical Sciences, Professor, Head of Ultrasonic Diagnostics Department, Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Russia, Kazan (munir.tuhbatullin@tatar.ru; ORCID: https://orcid.org/0000-0002-0055-4746)
- Fomina Elena E.
- Doctor of Medical Sciences, Associate Professor, Department of Ultrasound Diagnostics, Kazan State Medical Academy – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Russia, Kazan (efomina@mail.ru; ORCID: https://orcid.org/0000-0003-0667-6127)
Article link
Mukhametdinova L.M., Tukhbatullin M.G., Fomina E.E. The Importance of Ultrasound Examination of Renal Allograft [Electronic resource] // Acta medica Eurasica. – 2024. – №2. P. 27-33. – URL: https://acta-medica-eurasica.ru/en/single/2024/2/4/. DOI: 10.47026/2413-4864-2024-2-27-33.