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Speranskaya E.M., Saleeva A.F., Golubtsova N.N.
The Number of Mast Cells and Macrophages in Chronic Gingival Inflammation in Young People
Keywords: parodontitis, diode laser, mast cells, CD68, chronic inflammation of the gums, young people
The aim of this work was to study the number of mast cells and macrophages of the gingival lamina propria in young people in chronic inflammation. as a result of the study, new data were obtained on the distribution of mast cells and macrophages in the gum without inflammation. It is for the first time that the effect of microbial inflammation and laser therapy on resident cells of the connective gingival tissue is studied, those cells are part of the oral mucosal immune system, depending on the age. Gingival biopsy material obtained according to dental indications in patients aged 20–40 years was used in the work. CD68+ macrophages were detected by immunohistochemical method, the number and secretory activity of gingival mast cells were evaluated by staining with toluidine blue. The results of the conducted examinations showed that in parodontitis, the number of macrophages and degranulating mast cells in the connective tissue of the gingival lamina propria increases. the use of a diode laser in chronic parodontitis has an effect on the increase in the number of macrophages and gingival mast cells, but not on the degranulation process of mast cells.
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About authors
- Speranskaya Ekaterina M.
- Senior Lecturer, Post-Graduate Student, Department of General and Clinical Morphology and Forensic Medicine, Chuvash State University, Russia, Cheboksary (ne28@bk.ru; ORCID: https://orcid.org/0000-0003-0946-3434)
- Saleeva Albina F.
- Senior Lecturer, Department of General and Clinical Morphology and Forensic Medicine, Chuvash State University, Russia, Cheboksary (albina13_@mail.ru; ORCID: https://orcid.org/0000-0001-7956-8106)
- Golubtsova Natalya N.
- Doctor of Biological Sciences, Associate Professor, Head of the Department of General and Clinical Morphology and Forensic Medicine, Chuvash State University, Russia, Cheboksary (golubnata@list.ru; ORCID: https://orcid.org/0000-0002-5436-1333)
Article link
Speranskaya E.M., Saleeva A.F., Golubtsova N.N. The Number of Mast Cells and Macrophages in Chronic Gingival Inflammation in Young People [Electronic resource] // Acta medica Eurasica. – 2022. – №4. P. 65-72. – URL: https://acta-medica-eurasica.ru/en/single/2022/4/7/. DOI: 10.47026/2413-4864-2022-4-65-72.