UDC: 616.89-008: 615.214.32
BBC: 52.817.105
Malova A., Bulygina I., Nikitin L., Andreeva A., Ilyina S.
The Use of Antidepressants in Different Population Groups
Keywords: antidepressants, family doctors, children, elderly people, countries of the world (Russia).
The review article discusses various issues on the use of antidepressant in Europe, the United States, Australia and Canada. Antidepressants are among the most prescribed medications, as depression is currently the leading cause of disability and incapacity for working in the population. The article describes features of antidepressant prescribing by general practitioners, to whom patients with depression turn first of all. Depression most often affects women, middle-aged people and the elderly (senile), they are also the main consumers of antidepressants. Children and adolescents are also prescribed antidepressants (fluoxetine, sertraline or citalopram, others are not recommended) in connection with depression, anxiety, suicidal behavior, other mental disorders. In Russia and Chuvashia antidepressants are not prescribed as often as in developed countries, which is associated with psychiatric help seeking only in extreme cases. Rare use of new generation antidepressants (first-line medications for depression) in patients with mental disorders in our country is due to economic reasons and their periodic absence in the pharmacy network.
References
- Golenkov A.V. Osnovy psikhiatrii: sindromy i psikhotropnye sredstva [The basics of psychiatry: syndromes and psychotropic drugs]. Cheboksary, Chuvash University Publ., 2019, 104 p.
- Golenkov A.V., Safronov S.A., Kuznecov S.D. Rezul’taty odnodnevnoi perepisi bol’nykh s psikhicheskimi rasstroistvami v trekh psikhiatricheskikh bol’nitsakh Chuvashii [The results of a one-day census of patients with mental disorders in three psychiatric hospitals in Chuvashia]. Social’naya i klinicheskaya psihiatriya, 2015, vol. 25, no 3, pp. 56–60.
- Danilov D.S. Ot fluoksetina do estsitaloprama: sorokaletnyaya istoriya selektivnykh ingibitorov obratnogo neironal’nogo zakhvata serotonina i ikh znachenie dlya klinicheskoi praktiki na sovremennom etape razvitiya psikhofarmakoterapii depressii [From fluoxetine to escitalopram: a forty-year history of selective serotonin reuptake inhibitors and their implications for clinical practice at the present stage of development of psychopharmacotherapy for depression]. Dnevnik psihiatra, 2014, no. 2, pp. 4–7.
- Danilov D.S. Antidepressanty – ingibitory obratnogo zakhvata serotonina i noradrenalina: vzglyad cherez prizmu 30-letnei istorii [Antidepressants – Serotonin and Norepinephrine Reuptake Inhibitors: A Look Through the Prism of a 30-Year History]. Nevrologiya, nejropsihiatriya, 2018, vol. 10, no. 4, pp. 4–12.
- Danilov D.S. Istoriya tritsiklicheskikh antidepressantov i ee znachenie dlya sovremennoi psikhofarmakoterapii [The history of tricyclic antidepressants and its significance for modern psychopharmacotherapy]. Social’naya i klinicheskaya psikhiatriya, 2019, vol. 29, no. 2, pp. 65–78.
- Drobizhev M.Yu., Kikta S.V. Paroksetin: vysokaya chastota naznachenii [Paroxetine: high frequency of appointments]. Social’naya i klinicheskaya psikhiatriya, 2009, vol. 19, no. 3, pp. 55–59.
- Kubryak O.V. O metodakh diagnostiki pri naznachenii antidepressantov (mnenie vrachei) [On diagnostic methods for the appointment of antidepressants (doctors’ opinion)]. Sociologicheskie issledovaniya, 2010, no. 1(309), pp. 100–108.
- Lyubov E.B., Vas’kova L.B., Tyapkina M.V. Urovni suitsidov i potreblenie antidepressantov v Rossii i ee regionakh [Suicide levels and antidepressant consumption in Russia and its regions]. Suitsidologiya, 2017, vol. 8, no. 2(27), pp. 49–53.
- Aarts N., Noordam R., Hofman A., Tiemeier H., Stricker B.H., Visser L.E. Self-reported indications for antidepressant use in a populationbased cohort of middle-aged and elderly. J. Clin. Pharm, 2016, no. 38, pp. 1311–1317.
- Cameron I.M., Lawton K., Reid I.C. Appropriateness of antidepressant prescribing: an observational study in a Scottish primary-care setting. British J. General Practice, 2009, vol. 59(566), pp. 644–649.
- Clavenna A., Andretta M., Pilati P., Dusi M., Gangem M., Gattoni M., Lombardo G., Zoccante L., Bonati L., Bonati M. Antidepressant and antipsychotic use in an Italian pediatric population. BMC Pediatrics, 2011, vol. 11(4). Available at: http://www.biomedcentral.com/1471-2431/11/40.
- Forns J., Pottegård A., Reinders T., Poblador-Plou B., Morrose R., Brandt L., Cainzos-Achirica M., Hellfritzsch M., Schink T., Prados-Torres A., Giner-Soriano M., Hägg D., Hallas J., Cortés J., Jacquot E., Deltour N., Perez-Gutthann S., Pladevall M., Reutforsh J. Antidepressant use in Denmark, Germany, Spain, and Sweden between 2009 and 2014: Incidence and comorbidities of antidepressant initiators. Affective Disorders, 2019, no. 249, pp. 242–252.
- Frecceroa C., Sundquista K., Sundquista J., Jia J. Primary adherence to antidepressant prescriptions in primary health care: a population-based study in Sweden. Scandinavian J. primary health care, 2016, vol. 34, no. 1, pp. 83–88.
- Hartz I., Skurtveit S., Hjellvik V., Furu K., Nesvag R., Handal M. Antidepressant drug use among adolescents during 2004–2013: a population-based register linkage study. Acta Psychiatrica Scandinavica, 2016, no. 134, pp. 420–429. DOI: 10.1111/acps.12633.
- Hartz I., Skurtveit S., Steffenak A., Karlstad Q., Handal M. Psychotropic drug use among 0–17 year olds during 2004–2014: a nationwide prescription database study // BMC Psychiatry, 2016, vol. 16(1). DOI 10.1186/s12888-016-0716-x.
- Jakimavičius M., Sveikata A., Vainauskas P, Jankūnas R., Mikučionytė L., Sapolienė A., Šmigelskas K. Analysis of antidepressant prescribing tendencies in Lithuania in 2003–2004. Medicina (Kaunas), 2007, vol. 43, no. 5, pp. 412–418.
- Kaduševičius E., Mikučionytė L., Mačiulaitis R., Milvidaitė I., Sveikata A. Trends in the consumption of antidepressant drugs in Lithuania in 2002–2004. Medicina (Kaunas), 2006, vol. 42, no. 12, pp. 1020–1029.
- Mamdani M.M., Pharm D., Parikh S.V., Austin P.S., Upshur R. E.G. Use of Antidepressants Among Elderly Subjects: Trends and Contributing Factors. J. Psychiatry, 2000, vol. 157(3), pp. 360–366.
- Mars B., Heron J., Kessler D., Davies N.M., Martin R.M., Thomas K.H., Gunnell D. Influences on antidepressant prescribing trends in the UK: 1995–2011. Psychiatry Psychiatr. Epidemiol, 2017, no. 52, pp. 193–200. DOI 10.1007/s00127-016-1306-4.
- Martinsson G., Fagerberg I., Wiklund-Gustin L., Lindholm C. Specialist prescribing of psychotropic drugs to older persons in Sweden – a register-based study of 188 024 older persons. BMC Psychiatry, 2012, no. 12(197). Available at: http://www.biomedcentral.com/1471-244X/12/197.
- Mercier A., Auger-Aubin I., Lebeau J.-P., Royen P.V., Peremans L. Understanding the prescription of antidepressants: a Qualitative study among French GPs. BMC Family Practice, 2011, vol. 12(99). Available at: http://www.biomedcentral.com/1471-2296/12/99.
- Morrison J., Anderson M.-J., Sutton M., Munoz-Arroyo R., McDonald S., Maxwell M., Power A., Smith M., Wilson P. Factors influencing variation in prescribing of antidepressants by general practices in Scotland. British J. General Practice, 2009, vol. 59(559), pp. e25–31. DOI: 10.3399/bjgp 09X395076.
- Munoz-Arroyo R., Sutton M., Morrison J. Exploring potential explanations for the increase in antidepressant prescribing in Scotland using secondary analyses of routine data. British J. General Practice, 2006, vol. 56(527), pp. 423–428.
- Noufou Nana G., Doulougou B., Gomez F., Ylli A., Guralnik J., Zunzunegui M.V. Social differences associated with the use of psychotropic drugs among men and women aged 65 to 74 years living in the community: the international mobility in aging study (IMIAS). BMC Geriatrics, 2015, vol. 15(1), p. 85. DOI 10.1186/s12877-015-0083-3.
- Štimac D., Čulig J. Outpatient utilization of psychopharmaceuticals in the city of Zagreb 2001-2006. Psychiatria Danubina, 2009, vol. 21, no. 1, pp. 56–64.
- Švab1 V., Šubelj M., Vidmar G. Prescribing changes in anxiolytics and antidepressants in Slovenia. Psychiatria Danubina, 2011, vol. 23, no. 2, pp. 178–182.
- Téllez-Lapeiraa J., López-Torres Hidalgob J., García-Agua Solerc N., Gálvez-Alcarazd L., Escobar-Rabadánb F., García-Ruizc A. Prevalence of psychotropic medication use and associated factors in the elderly. J. Psychiat., 2016, vol. 30, no. 30, pp. 183–194.
- Vries Y.A., Jonge P., Kalverdijk L., Bos J., Schuiling-Veninga C., Hak E. Poor guideline adherence in the initiation of antidepressant treatment in children and adolescents in the Netherlands: choice of antidepressant and dose. Child Adolesc. Psychiatry, 2016, no. 25, pp. 1161–1168. DOI 10.1007/s00787-016-0836-3.
- Wijlaars L., Nazareth I., Petersen I. Trends in Depression an Antidepressant Prescribing in Children and Adolescents: A Cohort Study in The Health Improvement Network (THIN). Plos one, 2012, vol. 7(3), p. e33181.
- Wolf F., Freytag A., Schulz S., Lehmann T., Schaffer S., Vollmar H.C., Kühlein T., Gensichen J. German general practitioners’ self-reported management of patients with chronic depression. BMC Psychiatry, 2017, vol. 17(401). DOI 10.1186/s12888-017-1564-z.
- https://www.apteka.ua/article/260015.
- https://www.gazeta.ru/business/news/2019/10/20/n_13601114.shtml.
- https://takiedela.ru/news/2019/10/21/shalyat-nervishki.
- https://www.miloserdie.ru/article/antidepressanty-dlya-millionov-mif-tabletki-po-prezhnemu-rabotayut-ploho.
About authors
- Малова Анастасия Олеговна
- студентка V курса медицинского факультета, Chuvash State University, Russia, Cheboksary (sh.naastya@gmail.com; )
- Булыгина Ирина Евгеньевна
- кандидат медицинских наук, доцент кафедры психиатрии, медицинской психологии, неврологии, Chuvash State University, Russia, Cheboksary (ibuligina@rambler.ru; )
- Никитин Лев Николаевич
- кандидат медицинских наук, доцент кафедры психиатрии, медицинской психологии, неврологии, Chuvash State University, Russia, Cheboksary (pmp_chgu@mail.ru; )
- Андреева Алевтина Петровна
- ассистент кафедры психиатрии, медицинской психологии, неврологии, Chuvash State University, Russia, Cheboksary (alewtina.an@yandex.ru; )
- Ильина Светлана Иосифовна
- ассистент кафедры психиатрии, медицинской психологии, неврологии, Chuvash State University, Russia, Cheboksary (moi-zhiraf@mail.ru; )
Article link
Malova A., Bulygina I., Nikitin L., Andreeva A., Ilyina S. The Use of Antidepressants in Different Population Groups [Electronic resource] // Acta medica Eurasica. – 2019. – №4. P. . – URL: https://acta-medica-eurasica.ru/en/single/2019/4/2/.