UDC: 616.36-006.6-07
BBC: Р569.435.1-43
Timofeeva L.A., Sugutskiy A.G., Aleshina T.N.
Differential Diagnosis of Hepatocellular Cancer (a clinical case)
Keywords: hepatocellular cancer, multiparametric ultrasound, shear wave elastography, multispiral computed tomography
Hepatocellular carcinoma is a common cause of cancer deaths worldwide. Early detection of liver cancer can significantly improve the prognosis of the disease and patient survival. All methods of radiation diagnostics are used to diagnose hepatocellular cancer, each of which has its own advantages and limitations. To date, the method of choice in the differential diagnosis of liver pathology is a multiparametric ultrasound examination using new diagnostic techniques, which include shear wave elastography. This article demonstrates the opportunities of multiparametric ultrasound using shear wave elastography in the early differential diagnosis of hepatocellular cancer in a middle-aged patient without usual background changes in liver parenchyma.
References
- Berdnikov S.N., Sholokhov V.N., Sinyukova G.T. et al. Differentsial’naya diagnostika ochagovykh giperekhogennykh obrazovanii v pecheni [Differential Diagnostics of Liver Hyperechoic Lesions]. Koloproktologiya, 2017, no. 2(60), pp. 19–25.
- Karpin A.D., Starinskii V.V., Shakhzadova A.O. Zlokachestvennye novoobrazovaniya v Rossii v 2019 godu (zabolevaemost’ i smertnost’) [Malignant neoplasms in Russia in 2019 (morbidity and mortality)]. Moscow, 2020, 252 p.
- Danzanova T.Yu., Sinyukova G.T., Lepedatu P.I. et al. Kachestvennaya elastografiya s primeneniem tekhnologii ARFI v diagnostike novoobrazovanii pecheni [High-quality elastography using ARFI technology in the diagnosis of liver neoplasms]. Vestnik novykh meditsinskikh tekhnologii, 2014, no. 1. Available at: http://www.medtsu.tula.ru/VNMT/Bulletin/E2014-1/4941.pdf (Access Date: 2024, March 5).
- Morozova T.G. Sovershenstvovanie diagnosticheskikh algoritmov pri zabolevaniyakh pecheni, podzheludochnoi zhelezy i zhelchnykh protokov pri primenenii mul’tiparametricheskoi elastografii [Improvement of diagnostic algorithms in diseases of the liver, pancreas and bile ducts using multiparametric elastography]. Klinicheskaya praktika, 2017, no. 4(32), pp. 31–36.
- Borsukov A.V., Gorbatenko O.A., Venidiktova D.Yu. et al. Mul’tiparametricheskoe ul’trazvukovoe issledovanie v diagnostike gepatotsellyulyarnoi kartsinomy u patsienta bez tsirroza pecheni (klinicheskoe nablyudenie) [Multiparametric Ultrasound in the Diagnosis of Hepatocellular Carcinoma in a Patient Without Cirrhosis (Clinical Case)]. Onkologicheskii zhurnal: luchevaya diagnostika, luchevaya terapiya, 2020, vol. 3, no. 1, pp. 86–93. DOI: 10.37174/2587-7593-2020-3-1-86-93.
- Skuratov A.G., Lyzikov A.N., Svistunov S.V. Ul’trazvukovaya elastografiya dlya neinvazivnoi otsenki tsirroza pecheni i portal’noi gipertenzii [Ultrasound Elastography for Noninvasive Evaluation of Liver Cyrrosis and Portal Hypertension]. Problemy zdorov’ya i ekologii, 2017, no. 3(53), pp. 105–110.
- Nazarenko A.V., Tkachev S.I., Alieva S.B. et al. Sovremennye metodiki distantsionnoi luchevoi terapii v lechenii bol’nykh gepatotsellyulyarnym rakom [Modern methods of external-beam radiation therapy intreatment of patients with hepatocellular carcinoma]. Meditsinskii alfavit, 2019, vol. 1(10), pp. 29–34.
- Borsukov A.V., Aleksandrov Yu.K., Timofeeva L.A. et al. Elastografiya sdvigovykh voln: analiz klinicheskikh sluchaev [Shear wave elastography: case analysis]. Moscow, 2022, 468 p.
- Bleeker J.S., Quevedo J.F., Folpe A.L. Malignant’ perivascular epithelioid cell neoplasm: risk stratification and treatment strategies. Sarcoma, 2012, vol. 2012, 541626. DOI: 10.1155/2012/541626.
- Chartampilas E., Rafailidis V., Georgopoulou V. et al. Current Imaging Diagnosis of Hepatocellular Carcinoma. Cancers, 2022, vol. 14(16), 3997. DOI: 10.3390/cancers14163997.
- Chou R., Cuevas C., Fu R. et al. Imaging Techniques for the Diagnosis of Hepatocellular Carcinoma: A Systematic Review and Meta-analysis. Ann Intern Med., 2015, vol. 162(10), pp. 697–711. DOI: 10.7326/M14-2509.
- Marrero J.A., Kulik L.M., Sirlin C.B. et al. Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology, 2018, vol. 68(2), pp. 723–750. DOI: 10.1002/hep.29913.
- Nadarevic T., Giljaca V., Colli A. et al. Computed tomography for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease. Cochrane Database of Systematic Reviews 2021, Issue 10. Art. No.: CD013362. DOI: 10.1002/14651858.
- Nadarevic T., Colli A., Giljaca V. et al. Magnetic resonance imaging for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease. Cochrane Database of Systematic Reviews, 2021, iss. 5, Art. no. CD014798. DOI: 10.1002/14651858.CD014798.
- Clinical Practice Guidelines in Oncology. Hepatobiliary Cancers, version 4. 2021. Available at: https://www.nccn.org/professionals/physician_gls/pdf/hepatobiliary.pdf.
- Ronot M., Chernyak V., Burgoyne A. et al. Imaging to Predict Prognosis in Hepatocellular Carcinoma: Current and Future Perspectives. Radiology, 2023, vol. 307, no. 3. DOI: 10.1148/radiol.221429.
- Vogel A., Cervantes A., Chau I. et al. ESMO Guidelines Committee. Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol., 2018, vol. 29(4), pp. iv238–iv255. DOI: 10.1093/annonc/mdy308.
About authors
- Timofeeva Lyubov A.
- Doctor of Medical Sciences, Professor, Department of Propaedeutics of Internal Diseases with a Course of Radiation Diagnostics, Chuvash State University, Russia, Cheboksary (adabai@mail.ru; ORCID: https://orcid.org/0000-0002-4707-8214)
- Sugutskiy Aleksandr G.
- Radiologist, Republican Clinical Oncology Dispensary, Russia, Cheboksary (rkod@med.cap.ru; )
- Aleshina Tatiana N.
- Senior Lecturer, Department of Propaedeutics of Internal Diseases with a Course of Radiation Diagnostics, Chuvash State University, Russia, Cheboksary (brunetka08-87@mail.ru; ORCID: https://orcid.org/0000-0002-5068-7598)
Article link
Timofeeva L.A., Sugutskiy A.G., Aleshina T.N. Differential Diagnosis of Hepatocellular Cancer (a clinical case) [Electronic resource] // Acta medica Eurasica. – 2024. – №3. P. 81-86. – URL: https://acta-medica-eurasica.ru/en/single/2024/3/9/. DOI: 10.47026/2413-4864-2024-3-81-86.