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DOI: 10.47026/2413-4864-2024-1-1-9
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Diomidova V.N., Efimova O.A.

Analysis of Morphological Gastric Cancer Types

Keywords: cancer, stomach, morphological types, disease stages, localization of the tumor process, age of patients

Malignant neoplasms occupy the leading places in the structure of morbidity and mortality of the world's population. Stomach cancer is one of the five most common cancer types in Russia in terms of morbidity and is among the top three in terms of mortality from malignant neoplasms. The aim of the study is to study the morphological gastric cancer types depending on the stage, localization of the tumor process in the stomach and the age of the patient. Materials and methods. A retrospective analysis of data on 412 stomach cancer patients for 2022–2023, examined on the basis of the AI "Republican Clinical Oncology Dispensary" under the Health Ministry of Chuvashia, among whom there were 256 (62.1%) men and 156 (37.9%) women, was carried out. The average age of the patients was 65.6±12 years. All cases have morphological verification. Research results. The most frequently diagnosed morphological types of gastric cancer were identified: adenocarcinoma not otherwise specified (57.3%), colloid cancer (17.2%), less often – gastrointestinal stromal tumor (6.7%) squamous cell non-keratinizing carcinoma (4.1%). The remaining tumor types in gastric cancer were verified less frequently (0.2–3.0%). It was found that the most common morphological types of gastric cancer were detected in most cases in the elderly (over 60 years old) and males. Depending on the tumor localization in the stomach departments, it was verified: if the body of the stomach is affected, almost all types of stomach cancer are observed (the same with affection to the antrum), such types as tubular, micropapillary, neuroendocrine, scyrrhous and mixed were not found in the cardiac department of the stomach. In subtotal and total affection of all stomach parts, the morphological types of gastric cancer corresponded in most cases to not otherwise specified adenocarcinoma and colloid carcinoma. Such morphological type of gastric cancer as not otherwise specified adenocarcinoma which made up the bulk of all types of malignant gastric cancers, was mainly (in 52.1%) detected at stages III and IV of the disease and only in 16.9% of patients – at the early I stage of the disease. Other morphological types of gastric cancer identified in the late stages of the tumor process included colloid carcinoma, non-keratinizing squamous cell carcinoma and carcinoma simplex. Conclusions. The analysis of morphological gastric cancer types the predominance of adenocarcinomas and colloid cancer, identified more often in the late stages of the tumor process. The predominant localization of various morphological types of gastric cancer with body damage was established. The most common morphological types of gastric cancer are found in the elderly, more often in men.

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About authors

Diomidova Valentina N.
Doctor of Medical Sciences, Professor, Head of the Department of Propaedeutics of Internal Diseases with a Course of Radiation Diagnostics, Chuvash State University; Head of the Department of Ultrasound Diagnostics, City Clinical Hospital № 1, Russia, Cheboksary (diomidovavn@rambler.ru; ORCID: https://orcid.org/0000-0002-3627-7971)
Efimova Oksana A.
Radiologist, Republican Oncology Dispensary; Senior Lecturer,
Department of Propaedeutics of Internal Diseases with a Course of Radiation Diagnostics, Chuvash State University, Russia, Cheboksary (oksanalekseevna.e@gmail.com; ORCID: https://orcid.org/0000-0002-0624-4992)

Article link

Diomidova V.N., Efimova O.A. Analysis of Morphological Gastric Cancer Types [Electronic resource] // Acta medica Eurasica. – 2024. – №1. P. 1-9. – URL: https://acta-medica-eurasica.ru/en/single/2024/1/1/. DOI: 10.47026/2413-4864-2024-1-1-9.

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