Single article

DOI: 10.47026/2413-4864-2022-2-1-8

Zonov A.A., Nasyrova E.G., Leontiev E.A.

Changes in Psycho-Physiological Indicators after Training with the Use of Neuro-Biofeedback in People Who Had COVID-19

Keywords: biofeedback training, motivation, neuro-biofeedback, voluntary self-regulation, alpha-stimulating training

COVID-19 is an acute respiratory infection caused by SARS-CoV-2 coronavirus. The most common complications of this disease are viral pneumonia, acute respiratory failure and thromboembolism, up to 20% of patients suffer from long–term symptoms. The purpose of this study was to study the possibility of using neuro-biofeedback method in neuro-correction of patients who had suffered from COVID-19 disease with emotional disorders. The study involved 40 people (27 women and 13 men) who had suffered from COVID-19, experiencing emotional disorders and in need of rehabilitation, of whom 24 individuals made up the main group and 16 individuals – the control group. The age of the participants ranged from 25 to 73 years, the mean age was 42.25±2.59 years. Prior to the beginning and at the end of the study, both groups underwent tests: the "Depression Questionnaire", the State-Trait Anxiety Inventory, determination by the PSM-25 stress scale. The equipment "Neuro V" (Zelenograd, Russia) was used for neuro-biofeedback training. The neuro-feedback technology "Neuro V" makes it possible to use electroencephalography parameters for self-regulation. Stimulation of the alpha rhythm in the frequency range 8-14 Hz helped to change the psychoemotional state of the subjects. The changes were confirmed by valid diagnostic tests "Spielberger–Khanin Anxiety Scale", "Depression Questionnaire", indicators on PSM-25 stress scale, as well as a "subjective" decrease in the severity of the asthenic syndrome. The technique that we propose gave the opportunity to increase not only the indices of alpha rhythm power in the electroencephalography, but the subjective assessment of health as well.

References

  1. Bilinska K., von Bartheld C.S., Butowt R. Expression of the ACE2 Virus Entry Protein in the Nervus Terminalis Reveals the Potential for an Alternative Route to Brain Infection in COVID-19. Front Cell Neurosci., 2021, vol. 15, 674123. DOI: 10.3389/fncel.2021.674123.
  2. Cuiyan Wang et al. Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China. International Journal of Environmental Research and Public Health, 2020, vol. 17(5), p. 1729.
  3. Da Silveira M.P., da Silva Fagundes K.K., Bizuti M.R., Starck É. et al. Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current litera-ture. Clin Exp Med., 2021, vol. 21(1), pp. 15–28. DOI: 10.1007/s10238-020-00650-3.
  4. Davidson R.J., Lutz A. Buddha’s Brain: Neuroplasticity and Meditation. IEEE Signal Pro-cess Mag., 2008, vol. 25(1), pp. 176–174.
  5. England J.T., Abdulla A., Biggs C.M., Lee A.Y.Y. et al. Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes. Blood Rev., 2021, vol. 45, 100707. DOI: 10.1016/j.blre.2020.100707.
  6. Goyal M., Singh S., Sibinga E.M.S. et al. Meditation Programs for Psychological Stress and Well-being: A Systematic Review and Meta-analysis. JAMA Intern Med., 2014, vol. 174(3), pp. 357–368. DOI: 10.1001/jamainternmed.2013.13018.
  7. Greenberg J., Reiner K., Meiran N. “Mind the Trap”: Mindfulness Practice Reduces Cognitive Rigidity. PLOS ONE, 2012, vol. 7(5), e36206. DOI: https://doi.org/10.1371/journal.pone.0036206.
  8. Helms J., Kremer S., Merdji H., Clere-Jehl R. et al. Neurologic Features in Severe SARS-CoV-2 Infection. N Engl J Med., 2020, vol. 382(23), pp. 2268–2270. DOI: 10.1056/NEJMc2008597.
  9. Kanjanaumporn J., Aeumjaturapat S., Snidvongs K., Seresirikachorn K., Chusakul S. Smell and taste dysfunction in patients with SARS-CoV-2 infection: A review of epidemiology, patho-genesis, prognosis, and treatment options. Asian Pac J Allergy Immunol., 2020, vol. 38(2), pp. 69–77. DOI: 10.12932/AP-030520-0826.
  10. Kaur S., Bansal R., Kollimuttathuillam S., Gowda A.M. et al. The looming storm: Blood and cytokines in COVID-19. Blood Rev., 2021, vol. 46, 100743. DOI: 10.1016/j.blre.2020.100743.
  11. Kozlova L.I., Petrovskii E.D., Verevkin E.G., Mel’nikov M.E. et al. EEG Alpha-Rhythm-Related Changes in BOLD fMRI Signal in Neurofeedback Training. Bull Exp Biol Med., 2019, vol. 168(2), pp. 199–204. DOI: 10.1007/s10517-019-04674-y.
  12. Saussez S., Lechien J.R., Hopkins C. Anosmia: an evolution of our understanding of its importance in COVID-19 and what questions remain to be answered. Eur Arch Otorhinolaryngol., 2021, vol. 278(7), pp. 2187–2191. DOI: 10.1007/s00405-020-06285-0.
  13. Rajendran K., Krishnasamy N., Rangarajan J., Rathinam J., Natarajan M., Ramachandran A. Convalescent plasma transfusion for the treatment of COVID-19: Systematic review. J Med Virol., 2020, vol. 92(9), pp. 1475–1483. DOI: 10.1002/jmv.25961.
  14. Sattarzadeh Bardsiri M,. Kouhbananinejad S.M., Vahidi R., Soleimany S. et al. Ubiquitous convalescent plasma: An artificial universal plasma for COVID-19 patients. Transfus Apher Sci., 2021, vol. 60(5), 103188. DOI: 10.1016/j.transci.2021.103188.
  15. Zhang J.J., Dong X., Cao Y.Y. Yuan Y.D. et al. Clinical characteristics of 140 patients in-fected with SARS-CoV-2 in Wuhan, China. Allergy., 2020, vol. 75(7), pp. 1730–1741. DOI: 10.1111/all.14238.

About authors

Zonov Alexander A.
Lead Researcher, Neurobotics, Russia, Moscow (a.zonov@neurobotics.ru; ORCID: https://orcid.org/0000-0003-3751-2766)
Nasyrova Elena G.
Candidate of Medical Sciences, Lead Researcher, Neurobotics, Russia, Moscow (ORCID: https://orcid.org/0000-0002-3307-7077)
Leontiev Evgeny A.
Candidate of Medical Sciences, Associate Professor, Department of Normal and Topographic Anatomy, Chuvash State University, Russia, Cheboksary (lea737@yandex.ru; ORCID: https://orcid.org/0000-0002-7406-2074)

Article link

Zonov A.A., Nasyrova E.G., Leontiev E.A. Changes in Psycho-Physiological Indicators after Training with the Use of Neuro-Biofeedback in People Who Had COVID-19 [Electronic resource] // Acta medica Eurasica. – 2022. – №2. P. 1-8. – URL: http://acta-medica-eurasica.ru/en/single/2022/2/1/. DOI: 10.47026/2413-4864-2022-2-1-8.