Kuznetsov A.N., Belova A.N., Volovik M.G., Vorob’eva O.V., Khalak M.E.
Development of the Methodology for Studying the Social Attention of Children With Autism Spectrum Disorders by the Eye Tracking Method (Preliminary Results)
Development of social skills is an essential condition for the habilitation of children suffering from autism spectrum disorders (ASD). The method of eye tracking (ET) opens up great opportunities for studying social attention in this contingent of people with disabilities. The aim of the study is to form a set of stimulus materials for dynamic ET-testing of eye movement patterns that are sensitive to changes in the level of social attention in preschool-age children with ASD. The selection of stimulus content included the definition of requirements for the quality of the images presented, storage and encoding of stimuli, the development of the procedure for presenting stimuli and the methodology for processing the ET-data. The stimulus material was tested on a group of healthy adults. The developed approach to the formation of standardized stimulus content for testing the social attention of children with ASD by the eye tracking method takes into account the level of children's attention to images, the degree of differences in the results of ET obtained in children of typical development and in children with ASD, as well as the intensity of the dynamics in ET indicators in improvement of clinical indicators in children with ASD.
- Barabanshchikov V.A., Zhegallo A.V. Aytreking: metody registratsii dvizheny glaz v psikhologicheskikh issledovaniyakh i praktike [Eye tracking: methods of registering eye movements in psychological research and practice]. Moscow, Kogito-Tsentr, 2014, 126 p.
- Simashkova N.V., Makushkin Ye.V. Rasstroystva autisticheskogo spektra: diagnostika, lecheniye, nablyudeniye. Klinicheskiye rekomendatsii (protokol lecheniya) [Autism spectrum disorders: diagnosis, treatment, observation. Clinical recommendations (treatment protocol). Moscow, 50 p.
- Aresti-Bartolome N., Garcia-Zapirain B. Cognitive rehabilitation system for children with autism spectrum disorder using serious games: A pilot study. Mater. Eng., 2015, vol. 26, suppl. 1, pp. S811-S824. DOI: https://doi.org/10.3233/BME-151373.
- Avni I., Meiri G., Bar-Sinai A. et al. Children with autism observe social interactions in an idiosyncratic manner. Autism Res., 2020, vol. 13(6), pp. 935–946. DOI: https://doi.org/10.1002/aur.2234.
- Bacon E.C., Courchesne E., Barnes C.C. et al. Rethinking the idea of late autism spectrum disorder onset. Psychopathol., 2018, vol. 30(2), pp. 553–569. DOI: https://doi.org/10.1017/ S0954579417001067.
- Bird G., Press C., Richardson D.C. The role of alexithymia in reduced eye-fixation in autism spectrum conditions. Journal of Autism and Developmental Disorders, 2011, vol. 41(11), pp. 1556–1564. DOI: https://doi.org/ 10.1007/s10803-011-1183-3.
- Chawarska K., Macari S., Shic F. Context modulates attention to social scenes in toddlers with autism. Journal of Child Psychology and Psychiatry, 2012, vol. 53(8), pp. 903–913. DOI: https://doi.org/ 10.1111/j.1469-7610.2012.02538.x.
- Chita-Tegmark M. Social attention in ASD: A review and meta-analysis of eye-tracking studies. Dev. Disabil., 2016, vol. 48, pp. 79–93. DOI: https://doi.org/ 10.1016/j.ridd.2015.10.011.
- Dawson G., Sun J.M., Davlantis K.S. et al. Autologous cord blood infusions are safe and feasible in young children with autism spectrum disorder: results of a single-center phase I open-label trial. Stem Cells Transl. Med., 2017, vol. 6(5), pp. 1332–1339. DOI: https://doi.org/ 10.1002/sctm.16-0474.
- DiPietro J, Kelemen A, Liang Y, Sik-Lanyi C. Computer- and Robot-Assisted Therapies to Aid Social and Intellectual Functioning of Children with Autism Spectrum Disorder. Medicina (Kaunas), 2019, vol. 55(8), p. 440. DOI: https://doi.org/ 10.3390/medicina55080440.
- Duchowski A.T. Eye Tracking Methodology: Theory and Practice, 3rd Clemson, Clemson University, 2017, 418 p.
- Fletcher-Watson S., Leekam S.R., Benson V. et al. Eye-movements reveal attention to social information in autism spectrum disorder. Neuropsychologia, 2009, vol. 47(1), 248–257.
- Frazier T.W., Strauss M., Klingemier E.W. et al. A Meta-Analysis of Gaze Differences to Social and Nonsocial Information between Individuals with and without Autism. Am. Acad. Child Adolesc. Psychiatry, 2017, vol. 56(7), pp. 546–555. DOI: https://doi.org/ 10.1016/j.jaac.2017.05.005.
- Frye R.E. Social Skills Deficits in Autism Spectrum Disorder: Potential Biological Origins and Progress in Developing Therapeutic Agents. CNS Drugs, 2018, vol. 32(8), pp. 713–734. DOI: https://doi.org/10.1007/s40263-018-0556-y.
- Guimard-Brunault M., Hernandez N., Roché L. et al. Back to basic: do children with autism spontaneously look at screen displaying a face or an object? Autism Res. Treat., 2013, vol. 2013, DOI: https://doi.org/10.1155/2013/835247.
- Hanley M., McPhillips M., Mulhern G., Riby D.M. Spontaneous attention to faces in Asperger syndrome using ecologically valid static stimuli. Autism., 2013, vol. 17(6), pp. 754–761. DOI: https://doi.org/ 10.1177/1362361312456746.
- Hendry A., Jones E.J.H., Bedford R. et al. Developmental change in look durations predicts later effortful control in toddlers at familial risk for ASD. Neurodev. Disord., 2018, vol. 10(1), p. 3. DOI: https://doi.org/10.1186/s11689-017-9219-4.
- Klin A., Lin D.J., Gorrindo P. et al. Two-year-olds with autism orient to non-social contingencies rather than biological motion. Nature, 2009, vol. 459(7244), pp. 257–261. DOI: https://doi.org/ 10.1038/nature07868.
- Kou J., Le J., Fu M., Lan C., Chen Z., Li Q., Zhao W., Xu L., Becker B., Kendrick K.M. Comparison of three different eye-tracking tasks for distinguishing autistic from typically developing children and autistic symptom severity. Autism Res., 2019, vol. 12(10), pp. 1529–1540. DOI: https://doi.org/ 10.1002/aur.2174.
- McPartland J.C., Bernier R.A., Jeste S.S. et al. The Autism Biomarkers Consortium for Clinical Trials (ABC-CT): Scientiﬁc Context, Study Design, and Progress Toward Biomarker Qualiﬁ Front. Integr. Neurosci., 2020, vol. 14, p. 16. DOI: https://doi.org/10.3389/fnint.2020.00016.
- Nadig A., Lee I., Singh L. et al. How does the topic of conversation affect verbal exchange and eye gaze? A comparison between typical development and high-functioning autism. Neuropsychologia, 2010, vol. 48(9), pp. 2730–2739. DOI: https://doi.org/10.1016/j.neuropsychologia.2010.05.020.
- Ness S.L., Manyakov N.V., Bangerter A. et al. JAKE® Multimodal Data Capture System: Insights from an Observational Study of Autism Spectrum Disorder. Neurosci., 2017, vol. 11, p. 517. DOI: https://doi.org/ 10.3389/fnins.2017.00517.
- Pennisi P., Tonacci A., Tartarisco G., Billeci L., Ruta L., Gangemi S., Pioggia G. Autism and Social Robotics: A Systematic Review. Autism Res., 2016, vol. 9, pp. 165–183.
- Richey J.A., Damiano C.R., Sabatino A. et al. Neural Mechanisms of Emotion Regulation in Autism Spectrum Disorder. Autism Dev. Disord., 2015, vol. 45(11), pp. 3409–3423. DOI: https://doi.org/ 10.1007/s10803-015-2359-z.
- Strobl M.A.R., Lipsmeier F., Demenescu L.R., Gossens C., Lindemann M., De Vos M. Look me in the eye: evaluating the accuracy of smartphone-based eye tracking for potential application in autism spectrum disorder research. Eng. Online., 2019, vol. 18(1), p. 51. DOI: https://doi.org/ 10.1186/s12938-019-0670-1.
- Tsang V., Chu P.C.K. Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos. Vis. Exp., 2018, no. 142. DOI: 10.3791/58694.https://doi.org/10.3791/58694.
- Stagg S.D., Linnell K.J., Heaton P. Investigating eye movement patterns, language, and social ability in children with autism spectrum disorder. Development and Psychopathology, 2014, no. 26(02), pp. 529–537.
- Wang Q., Chang J., Chawarska K. Atypical Value-Driven Selective Attention in Young Children with Autism Spectrum Disorder. JAMA Netw Open., 2020, vol. 3(5), e204928. DOI: https://doi.org/ 10.1001/jamanetworkopen.2020.4928.
- Kuznetsov Alexey N.
- Minor Researcher of Departments of Functional Diagnostics, Privolzhsky Research Medical University (PIMU), Russia, Nizhny Novgorod (firstname.lastname@example.org; ORCID: https://orcid.org/0000-0003-1889-1297)
- Belova Anna N.
- Doctor of Medical Sciences, Professor, Head of Departments of Medical Rehabilitation, Privolzhsky Research Medical University (PIMU), Russia, Nizhny Novgorod (email@example.com; ORCID: https://orcid.org/0000-0001-9719-6772)
- Volovik Mikhail G.
- Doctor of Biological Sciences, Leading Researcher of Departments of Functional Diagnostics, Privolzhsky Research Medical University (PIMU), Russia, Nizhny Novgorod (firstname.lastname@example.org; ORCID: https://orcid.org/0000-0002-3230-6990)
- Vorob’eva Olga V.
- Minor Researcher of Departments of Functional Diagnostics, Privolzhsky Research Medical University (PIMU), Russia, Nizhny Novgorod (email@example.com; ORCID: https://orcid.org/0000-0001-7225-8842)
- Khalak Maria E.
- Candidate of Psychological Sciences, Assistant Lecturer, Department of General and Clinical Psychology, Privolzhsky Research Medical University (PIMU), Russia, Nizhny Novgorod (firstname.lastname@example.org; ORCID: https://orcid.org/0000-0003-1897-8894)
Kuznetsov A.N., Belova A.N., Volovik M.G., Vorob’eva O.V., Khalak M.E. Development of the Methodology for Studying the Social Attention of Children With Autism Spectrum Disorders by the Eye Tracking Method (Preliminary Results) [Electronic resource] // Acta medica Eurasica. – 2021. – №2. P. 17-27. – URL: http://acta-medica-eurasica.ru/en/single/2021/2/3/. DOI: 10.47026/2413-4864-2021-2-17-27.