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Yalaletdinova l., Gordova V., Yastrebova S., Sergeeva V.
Morphological characteristics of nonpregnant mice thymus at chorionic gonadotropin injection
Keywords: thymus, chorionic gonadotropin, lymphocytes
The given work is dedicated to morphological and immunohistochemical characteristics of the thymus of mice (n = 100) at chorionic gonadotropin injection during 1, 2, 3, 4 weeks in the dose of 2 IU/mouse twice a week. Monoclonal antibodies to receptors CD4, CD8, protein Ki-67 to evaluate the proliferative pool of lymphocytes were used. Hormone injection leads to changing the form and to an increase in medulla’s area in thymic lobules, to an increase of the amount of CD4+ and CD8+ cells in lobules of thymus. Along with this a reduction in the number of cells expressing the protein of proliferation Ki-67 takes place.
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About authors
- Gordova Valentina S.
-
Candidate of Medical Sciences, Associate Professor, Department
of Fundamental Medicine, Immanuel Kant Baltic Federal University, Russia, Kaliningrad (crataegi@rambler.ru; ORCID: https://orcid.org/0000-0001-5109-9862)
- Sergeeva Valentina E.
- Doctor of Biological Sciences, Professor, Department of Medical Biology with a course in Microbiology and Virology, Chuvash State University, Russia, Cheboksary (kaf-biology@yandex.ru; ORCID: https://orcid.org/0000-0003-3471-5226)
- Yastrebova Svetlana A.
- Candidate of Biological Sciences, Associate Professor of the Department of Medical Biology with a course in Microbiology and Virology, Chuvash State University, Russia, Cheboksary (kaf-biology@yandex.ru; )
- Yalaletdinova Leysan Ramilovna
- candidate of medical sciences, obstetrician-gynecologist, Chuvash State University, Russia, Cheboksary (barbaris09@bk.ru; )
Article link
Yalaletdinova l., Gordova V., Yastrebova S., Sergeeva V. Morphological characteristics of nonpregnant mice thymus at chorionic gonadotropin injection [Electronic resource] // Acta medica Eurasica. – 2016. – №3. P. 59-65. – URL: https://acta-medica-eurasica.ru/en/single/2016/3/10/.