Single article

Kostrova O., Stomenskaya I., Merkulova L., Struchko G., Kotelkina A., Mikhailova M.

Response of adrenal biogenic amines in female rats to water-immobilization stress

Keywords: adrenal glands, rats, stress, histamine (HST), serotonin (ST), catecholamines (CAs), luminescent granular cells

Adrenal glands of 30 female rats were examined using luminescent-histochemical methods. The animals were divided into two groups: control rats and rats, which were subjected to water-immobilization stress lasting one hour daily during the period of 10 days. Animals were removed from the experiment in 30, 60 and 90 days after the end of exposure. It was found that the effect of water-immobilization stress changed the level of biogenic amines in the adrenal glands, the organ weight, the ratio (ST+HST)/CA and the number of luminescent granular cells. All these changes are of undulating nature and depend on the period of the study. It is probable that the alert stage developed in rats in 30 days after the end of exposure. In 60 days the stage of exhaustion begins. On the 90th day the stage of recovery forms in rats.

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About authors

Kostrova Olga Yu.
Candidate of Medical Sciences, Assistant Professor, Head of Department of the Instrumental Diagnostics with a Course of Phthisiology, Chuvash State University, Russia, Cheboksary (evkbiz@yandex.ru)
Struchko Gleb Yu.
Doctor of Medical Sciences, Professor, Head of Normal and Topographic Anatomy Department, Chuvash State University, Russia, Cheboksary (glebstr@mail.ru)
Stomenskaya Irina S.
Candidate of Medical Sciences, Assistant Professor, Department of the Instrumental Diagnostics with a Course of Phthisiology, Chuvash State University, Russia, Cheboksary (irina.stomenskaja@gmail.com)
Merkulova Larisa M.
Doctor of Medical Sciences, Professor of Normal and Topographic Anatomy Department, Chuvash State University, Russia, Cheboksary (merkulova192@mail.ru)
Mikhailova Marina A.
Candidate of Medical Sciences, Assistant Professor, Normal and Topographic Anatomy Department, Chuvash State University, Russia, Cheboksary (mar3007@mail.ru)
Kotelkina Anastasia
normal and topographic anatomy with operative surgery department assistant , Chuvash State University, Russia, Cheboksary

Article link

Kostrova O., Stomenskaya I., Merkulova L., Struchko G., Kotelkina A., Mikhailova M. Response of adrenal biogenic amines in female rats to water-immobilization stress [Electronic resource] // Acta medica Eurasica. – 2018. – №3. P. 34-39. – URL: http://acta-medica-eurasica.ru/en/single/2018/3/5/.