Single article

Lutkova Т., Karzakova L., Ukhterova N., Zhuravleva N., Andreeva N., Kudryashov S., Pavlova Z.

Description of a Clinical Case of Lyell's Syndrome in a Child

Keywords: toxic epidermal necrolysis, Lyell's syndrome, drug-induced disease

Toxic epidermal necrolysis is a variant of an allergic disease, which is potentially life-threatening due to disorders characterized by widespread epidermal necrolysis, mucosal erosion and severe systemic symptoms. Issues of epidemiology, features of clinical course of toxic epidermal necrolysis (Lyell's syndrome) in children are insufficiently covered in domestic and world literature. Children are known to develop this disease against the background of an infectious process which is associated in the predominant number of cases with such an infectious pathogen as St. aureus. The article presents its own clinical description of Lyell's syndrome in a child, the cause of which was the drug Actovegin which is often used in pediatric practice. The article presents the analysis of the carried – out therapy from the moment of the child's admission to the medical institution which provided a favorable outcome – full recovery of the child. The description of the given clinical case is confirmed by available literature data on the duration of hospital treatment, the need to use different groups of expensive drugs in the treatment of patients with Lyell's syndrome.

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About authors

Lutkova Tatyana S.
Candidate of Medical Sciences, Associate Professor of Internal Diseases Department, Chuvash State University, Russia, Cheboksary (lts21@mail.ru)
Karzakova Luiza M.
Doctor of Medical Sciences, Professor, Head of Internal Diseases Department, Chuvash State University, Russia, Cheboksary (luizak58@mail.ru)
Ukhterova NadezhdaD.
Candidate of Medical Sciences, Associate Professor of Internal Medicine Department, Chuvash State University, Russia, Cheboksary (55dd@mail.ru)
Zhuravleva Nadezhda V.
Candidate of Medical Sciences, Associate Professor of Internal Medicine Department, Chuvash State University, Russia, Cheboksary (zhuravlevanv@mail.ru)
Andreeva Natalia
candidate of medical sciences, pediatrics and pediatric surgery department associate professor, Chuvash State University, Russia, Cheboksary (kafedrapediatrii@mail.ru)
Kudryashov Sergei I.
Candidate of Medical Sciences, Associate Professor of Internal Diseases Department, Chuvash State University, Russia, Cheboksary (medicpro21@mail.ru)
Pavlova Zinaida
Clinical Laboratory Diagnostics Doctor, Central City Hospital, Russia, Cheboksary (cgb@med.cap.ru)

Article link

Lutkova Т., Karzakova L., Ukhterova N., Zhuravleva N., Andreeva N., Kudryashov S., Pavlova Z. Description of a Clinical Case of Lyell’s Syndrome in a Child [Electronic resource] // Acta medica Eurasica. – 2019. – №3. P. 15-23. – URL: http://acta-medica-eurasica.ru/en/single/2019/3/3/.